Characterization of functional domains of the teir protein which regulates testosterone-induced expression of 3α-hydroxysteroid dehydrogenase/carbonyl reductase in Comamonas testosteroni

被引：0
|
作者：
Maser, E. [1 ]
Trentmann, G. [1 ]
Paulsen, S. [1 ]
Goehler, A. [1 ]
Xiong, G. [1 ]
机构：
[1] Univ Med Sch Schleswig Holstein, Inst Toxicol & Pharmacol Nat Sci, D-24105 Kiel, Germany
来源：
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 2007年 / 375卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
517
引用
收藏
页码：101 / 102
页数：2
相关论文
共 31 条
  • [21] Role of Lysl 59 in the proton relay system of the 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni
    Hwang, Chi-Ching
    Chang, Yi-Hsun
    FASEB JOURNAL, 2007, 21 (05): : A273 - A273
  • [22] Structural aspects of oligomerization in 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni:: New approaches for efficient protein design
    Hoffmann, F
    Sotriffer, C
    Evers, A
    Xiong, GM
    Maser, E
    Enzymology and Molecular Biology of Carbonyl Metabolism 12, 2006, 12 : 308 - 314
  • [23] Identification and Characterization of the LysR-Type Transcriptional Regulator HsdR for Steroid-Inducible Expression of the 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase Gene in Comamonas testosteroni
    Gong, Wenjie
    Xiong, Guangming
    Maser, Edmund
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2012, 78 (04) : 941 - 950
  • [24] Characterization of repressors RepA and RepB of the steroid-inducible 3α-hydroxysteroid dehydrogenase/carbonyl reductase in Comamonas testosteroni by gene knock out studies
    Xiong, GM
    Schüller, C
    Döring, B
    Maser, E
    Enzymology and Molecular Biology of Carbonyl Metabolism 12, 2006, 12 : 315 - 323
  • [25] Role of S114 in the NADH-induced conformational change and catalysis of 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni
    Chang, Yi-Hsun
    Huang, Tzu-Jung
    Chuang, Lea-Yea
    Hwang, Chi-Ching
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2009, 1794 (10): : 1459 - 1466
  • [26] 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni:: biological significance, three-dimensional structure and gene regulation
    Maser, E
    Xiong, GM
    Grimm, C
    Ficner, R
    Reuter, K
    CHEMICO-BIOLOGICAL INTERACTIONS, 2001, 130 (1-3) : 707 - 722
  • [27] The crystal structure of 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family
    Grimm, C
    Maser, E
    Möbus, E
    Klebe, G
    Reuter, K
    Ficner, R
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (52) : 41333 - 41339
  • [28] Molecular cloning overexpression, and characterization of steroid-inducible 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni -: A novel member of the short-chain dehydrogenase/reductase superfamily
    Möbus, E
    Maser, E
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (47) : 30888 - 30896
  • [29] Mechanistic roles of Ser-114, Tyr-155, and Lys-159 in 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni
    Hwang, CC
    Chang, YH
    Hsu, CN
    Hsu, HH
    Li, CW
    Pon, HI
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (05) : 3522 - 3528
  • [30] The Catalytic Roles of P185 and T188 and Substrate-Binding Loop Flexibility in 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni
    Hwang, Chi-Ching
    Chang, Yi-Hsun
    Lee, Hwei-Jen
    Wang, Tzu-Pin
    Su, Yu-Mei
    Chen, Hsin-Wei
    Liang, Po-Huang
    PLOS ONE, 2013, 8 (05):
1234