ImmunoMagnetical Reduction Using High Tc Superconducting Quantum Interference Device (SQUID)

被引：0
|
作者：
Chieh, J. J. [1 ]
Chen, C. H. [1 ]
Yang, S. Y. [1 ]
Horng, H. E. [1 ]
Yang, H. C. [2 ]
Hong, Chin-Yih [3 ]
机构：
[1] Natl Taiwan Normal Univ, Inst Electroopt Sci & Technol, Taipei, Taiwan
[2] Natl Taiwan Univ, Dept Phys, Taipei, Taiwan
[3] Nan Kai Inst Technol, Dept Mech Engn, Caotun, Nantou, Taiwan
来源：
2009 9TH IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOENGINEERING | 2009年
关键词：
ac magnetoreduction; SQUID; magnetic nanoparticles;
D O I：
10.1109/BIBE.2009.81
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
In this work, we develop a platform for assaying biomolecules involving the measurement of alternating current ac magnetoreduction of magnetic reagent mixed with a detected sample. The magnetic reagent contains magnetic nanoparticles coated with a given kind of antibody, which associates with conjugated biomolecules. Then, the biomolecules can be quantitatively detected by measuring the ac magnetoreduction of magnetic reagent. To achieve hyper-high-sensitivity assay, a system utilizing a high-transition-temperature rf superconducting quantum interference device (SQUID) as a sensor to probe the magnetoreduction of reagent due to the association between biomolecules and magnetic nanoparticles. Examples to assay human CRP are given to demonstrate the validity of
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页码：364 / +
页数：2
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