Serum amino-terminal pro-brain natriuretic peptide in hematological patients with neutropenic fever: a prospective comparison with C-reactive protein

被引：9
|
作者：
Hamalainen, Sari [1 ]
Juutilainen, Auni [1 ,2 ]
Kuittinen, Taru [1 ]
Nousiainen, Tapio [1 ]
Matinlauri, Irma [3 ]
Pulkki, Kari [4 ,5 ]
Koivula, Irma [1 ]
Jantunen, Esa [1 ,2 ]
机构：
[1] Kuopio Univ Hosp, Dept Med, Kuopio 70211, Finland
[2] Univ Eastern Finland, Inst Clin Med Internal Med, Kuopio, Finland
[3] Turku Univ, Cent Hosp, Dept Clin Chem, Turku, Finland
[4] Univ Eastern Finland, Eastern Finland Lab Ctr, Kuopio, Finland
[5] Univ Eastern Finland, Dept Clin Chem, Kuopio, Finland
来源：
LEUKEMIA & LYMPHOMA | 2010年 / 51卷 / 06期
关键词：
N-terminal pro-BNP; C-reactive protein; neutropenic fever; severe sepsis; hematological patients; CRITICALLY-ILL PATIENTS; SEVERE SEPSIS; SEPTIC SHOCK; FEBRILE NEUTROPENIA; PROGNOSTIC VALUE; BNP; DEFINITIONS; DYSFUNCTION; GUIDELINES; FAILURE;
D O I：
10.3109/10428191003743478
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Serum amino-terminal pro-brain natriuretic peptide (NT-proBNP) is considered as a prognostic marker in patients with severe sepsis or septic shock, but no data are available on NT-proBNP kinetics in hematological patients with neutropenic fever. Altogether 70 hematological patients with neutropenic fever were included in this prospective study. NT-proBNP and C-reactive protein (CRP) were determined at the beginning of the neutropenic fever (d0) and then daily up to 3-4 days. The median NT-proBNP (interquartile range) increased from 127 (57-393) ng/L on d0 to 542 (194-1385) ng/L on d4. The increment of CRP was from 35 (17-61) mg/L on d0 to 109 (56-109) mg/L on d2. Neither serial NT-proBNP nor CRP predicted development of severe sepsis, but NT-proBNP was significantly higher in patients with previous cardiovascular disease than in those without. NT-proBNP seemed to reflect cardiac distress, but it did not help to predict the development of severe sepsis in this patient group.
引用
收藏
页码：1040 / 1046
页数：7
相关论文
共 50 条
  • [21] Multiplexed Determination of Amino-Terminal Pro-BType Natriuretic Peptide and C-Reactive Protein Cardiac Biomarkers in Human Serum at a Disposable Electrochemical Magnetoimmunosensor
    Esteban-Fernandez de Avila, Berta
    Escamilla-Gomez, Vanessa
    Lanzone, Valentina
    Campuzano, Susana
    Pedrero, Maria
    Compagnone, Dario
    Pingarron, Jose M.
    ELECTROANALYSIS, 2014, 26 (02) : 254 - 261
  • [22] Usefulness of N-terminal pro-brain natriuretic peptide and C-reactive protein to predict ICU mortality in unselected medical ICU patients: a prospective, observational study
    Feilong Wang
    Wenzhi Pan
    Shuming Pan
    Shuyun Wang
    Qinmin Ge
    Junbo Ge
    Critical Care, 15
  • [23] Usefulness of N-terminal pro-brain natriuretic peptide and C-reactive protein to predict ICU mortality in unselected medical ICU patients: a prospective, observational study
    Wang, Feilong
    Pan, Wenzhi
    Pan, Shuming
    Wang, Shuyun
    Ge, Qinmin
    Ge, Junbo
    CRITICAL CARE, 2011, 15 (01):
  • [24] Normal amino-terminal pro-brain natriuretic peptide (NT-proBNP) values in amniotic fluid
    Andres Carvajal, Jorge
    Andres Ferrer, Fernando
    Isabel Araya, Francisca
    Maria Delpiano, Ana
    CLINICAL BIOCHEMISTRY, 2017, 50 (1-2) : 23 - 26
  • [25] Umbilical cord blood amino-terminal pro-brain natriuretic peptide levels according to the mode of delivery
    Seong, Won Joon
    Yoon, Douk Hun
    Chong, Gun Oh
    Hong, Dae Gy
    Koo, Tae Bon
    Lee, Taek Hoo
    Chun, Sang Sik
    ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2010, 281 (05) : 907 - 912
  • [26] Prognostic value of plasma amino-terminal pro-brain natriuretic peptide in a large, representative ICU population
    A Kotanidou
    P Karsaliakos
    M Tzanela
    I Mavrou
    P Kopterides
    E Papadomichelakis
    M Theodorakopoulou
    I Tsagaris
    M Lignos
    I Ikonomidis
    I Ilias
    A Armaganidis
    S Orfanos
    I Dimopoulou
    Critical Care, 12 (Suppl 2):
  • [27] Umbilical cord blood amino-terminal pro-brain natriuretic peptide levels according to the mode of delivery
    Won Joon Seong
    Douk Hun Yoon
    Gun Oh Chong
    Dae Gy Hong
    Tae Bon Koo
    Taek Hoo Lee
    Sang Sik Chun
    Archives of Gynecology and Obstetrics, 2010, 281 : 907 - 912
  • [28] Amino-terminal pro-brain natriuretic peptide to diagnose congestive heart failure in patients with impaired kidney function - Reply
    Januzzi, James L.
    Lloyd-Jones, Donald M.
    Anwaruddin, Saif
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (05) : 1061 - 1061
  • [29] Amino-terminal pro-brain natriuretic peptide for the diagnosis of acute heart failure in patients with previous obstructive airway disease
    Tung, Roderick H.
    Camargo, Carlos A., Jr.
    Krauser, Dan
    Anwaruddin, Saif
    Baggish, Aaron
    Chen, Annabel
    Januzzi, James L., Jr.
    ANNALS OF EMERGENCY MEDICINE, 2006, 48 (01) : 66 - 74
  • [30] Amino-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) Serum Levels in Females with Different Thyroid Function States
    Hadzovic-Dzuvo, Almira
    Kucukalic-Selimovic, Elma
    Nakas-Icindic, Emina
    Lepara, Orhan
    Valjevac, Amina
    Rasic, Senija
    Al Tawil, Dinan
    Begic, Amela
    Sofic, E.
    TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, 2011, 36 (02): : 116 - 121
12345