Synthesis of guanidine derivatives and molecular recognition

被引:6
|
作者
Qi, YX [1 ]
Gao, HX [1 ]
Yang, M [1 ]
Xia, CG [1 ]
Suo, J [1 ]
机构
[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo SYntheis & Select Oxidat, Lanzhou 730000, Peoples R China
关键词
D O I
10.1081/SCC-120017128
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Five Guanidine Derivatives bearing acyl group were synthesized by the reaction of acyl chloride with 1,1,3,3-tetramethylguanidine. Their structures were confirmed by IR, H-1-NMR, EI-MS, HRMS and elementary analysis. One of them (4a) was also characterized by X-ray. Preliminary results of interaction with phosphate-containing biomolecules and adipate showed that all of them exhibited the abilities of molecular recognition.
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页码:1073 / 1079
页数:7
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