Modulation of long-interval intracortical inhibition and the silent period by voluntary contraction

被引:33
|
作者
Hammond, Geoffrey [1 ]
Vallence, Ann-Maree [1 ]
机构
[1] Univ Western Australia, Sch Psychol, Crawley, WA 6009, Australia
关键词
motor cortex; transcranial magnetic stimulation; intracortical inhibition; LICI; silent period; voluntary movement;
D O I
10.1016/j.brainres.2007.05.014
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Transcranial magnetic stimulation was used to examine the effect of voluntary contraction on the magnitude of long-interval intracortical inhibition (LICI) and the duration of the silent period in intrinsic hand muscles. The magnitude of LICI acting on the first dorsal interosseus (FDI) measured with a paired-pulse protocol with an inter-pulse interval of 100 ms decreased with increasing tonic level of voluntary abduction force generated by the index finger. LICI in abductor pollicis brevis (APB) decreased from the condition in which the index finger was at rest to the conditions in which it was abducted, whereas LICI in abductor digiti minimi (ADM) was unaffected by the level of index finger abduction. During voluntary abduction of the index finger, the magnitude of LICI was least in FDI, intermediate in ADM, and greatest in APB, suggesting that it may be a mechanism by which tonic activation of hand muscles is fractionated. The magnitude of LICI increased with conditioning stimulus intensity, but intensity did not interact with abduction force. The duration of the silent period (SP) in FDI decreased with the level of voluntary index finger abduction and increased with eliciting stimulus intensity. Within-subject correlations showed that the effects of voluntary drive on SP duration and motor-evoked potential amplitude did not covary, implying an indirect effect of voluntary drive on SP duration. It is proposed that whereas voluntary drive directly reduces the magnitude of slow-acting inhibition acting on the active movement representations and near neighbors, sensory feedback from the contracting muscle acts to limit its time course. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:63 / 70
页数:8
相关论文
共 50 条
  • [41] Reliability of Long-Interval Cortical Inhibition in Healthy Human Subjects: A TMS-EEG Study
    Farzan, Faranak
    Barr, Mera S.
    Levinson, Andrea J.
    Chen, Robert
    Wong, Willy
    Fitzgerald, Paul B.
    Daskalakis, Zafiris J.
    JOURNAL OF NEUROPHYSIOLOGY, 2010, 104 (03) : 1339 - 1346
  • [42] Short-interval cortical inhibition and intracortical facilitation during submaximal voluntary contractions changes with fatigue
    Sandra K. Hunter
    Chris J. McNeil
    Jane E. Butler
    Simon C. Gandevia
    Janet L. Taylor
    Experimental Brain Research, 2016, 234 : 2541 - 2551
  • [43] Short-interval cortical inhibition and intracortical facilitation during submaximal voluntary contractions changes with fatigue
    Hunter, Sandra K.
    McNeil, Chris J.
    Butler, Jane E.
    Gandevia, Simon C.
    Taylor, Janet L.
    EXPERIMENTAL BRAIN RESEARCH, 2016, 234 (09) : 2541 - 2551
  • [44] Interhemispheric inhibition by voluntary motor cortex activation measured by enhancement of the ipsilateral silent period
    Cincotta, M.
    Giovannelli, F.
    Borgheresi, A.
    Balestrieri, F.
    Zaccara, G.
    Viggiano, M. P.
    Ziemann, U.
    EUROPEAN JOURNAL OF NEUROLOGY, 2009, 16 : 24 - 24
  • [45] Long-interval facilitation and inhibition are differentially affected by conditioning stimulus intensity over different time courses
    Vallence, Ann-Maree
    Schneider, Luke A.
    Pitcher, Julia B.
    Ridding, Michael C.
    NEUROSCIENCE LETTERS, 2014, 570 : 114 - 118
  • [46] Reduced silent period of facial muscles in migraine:: thalamo-cortical hypoactivity or true decreased intracortical inhibition?
    Coppola, G.
    Curra, A.
    Barbanti, P.
    Buzzi, M. G.
    Galeotti, F.
    Serrao, M.
    Truini, A.
    Pierelli, F.
    Cruccu, G.
    CEPHALALGIA, 2006, 26 (11) : 1388 - 1388
  • [47] Long-interval afferent inhibition measurement using two different methods: Normative values, repeatability and reliability
    Boran, Hurrem Evren
    Alayd, Halil Can
    Kilinc, Hasan
    Tankisi, Hatice
    Samusyte, Ginte
    Howells, James
    Koltzenburg, Martin
    Cengiz, Bulent
    NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY, 2024, 54 (01):
  • [48] Mechanisms underlying long-interval cortical inhibition in the human motor cortex: a TMS-EEG study
    Rogasch, Nigel C.
    Daskalakis, Zafiris J.
    Fitzgerald, Paul B.
    JOURNAL OF NEUROPHYSIOLOGY, 2013, 109 (01) : 89 - 98
  • [49] Modulation of interhemispheric inhibition by volitional motor activity: an ipsilateral silent period study
    Giovannelli, Fabio
    Borgheresi, Alessandra
    Balestrieri, Fabrizio
    Zaccara, Gaetano
    Viggiano, Maria Pia
    Cincotta, Massimo
    Ziemann, Ulf
    JOURNAL OF PHYSIOLOGY-LONDON, 2009, 587 (22): : 5393 - 5410
  • [50] Assessment of post-excitatory long-interval cortical inhibition in adult attention-deficit/hyperactivity disorder
    Retz, Wolfgang
    Gonzalez-Trejo, Ernesto
    Roemer, Konstanze D.
    Philipp-Wiegmann, Florence
    Reinert, Philip
    Low, Yin Fen
    Boureghda, Samir
    Roesler, Michael
    Strauss, Daniel J.
    EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 2012, 262 (06) : 507 - 517