Synthesis of new indolylpyrrole derivatives via a four-component domino reaction between arylglyoxals, acetylacetone, indole and aliphatic amines in aqueous media

被引:11
|
作者
Mousavizadeh, Fereshteh [1 ]
Talebizadeh, Mahdiyeh [1 ]
Anary-Abbasinejad, Mohammad [1 ]
机构
[1] Vali e Asr Univ, Dept Chem, Rafsanjan 77176, Iran
关键词
Indolylpyrrole; Four-component reaction; Arylglyoxal; Aqueus media; Synthesis; MARTEFRAGIN;
D O I
10.1016/j.tetlet.2018.06.043
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel synthesis of indolylpyrrole derivatives is described by a four-component domino reaction between arylglyoxals, acetylacetone, indole and aliphatic amines in water as solvent at 60 degrees C without using any catalyst or promoter. The FT-IR, H-1 NMR, C-13 NMR spectral and elemental analysis confirm the structures of the products. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2970 / 2974
页数:5
相关论文
共 50 条
  • [41] Synthesis of some new triamide derivatives via Ugi five-component reaction in aqueous solution
    Ali Asghar Mohammadi
    Salman Taheri
    Arman Amini
    Reza Ahdenov
    Molecular Diversity, 2018, 22 : 999 - 1006
  • [42] One-pot synthesis of functionalized hydantoin derivatives via a four-component reaction between an amine, an arylsulfonyl isocyanate and an alkyl propiolate or dialkyl acetylenedicarboxylate in the presence of triphenylphosphine
    Alizadeh, Abdolah
    Sheikhi, Ehsan
    TETRAHEDRON LETTERS, 2007, 48 (28) : 4887 - 4890
  • [43] Efficient synthesis of new pyrano[2,3-d]pyrimidine-2,4-dione derivatives via a one-pot four-component reaction
    Sharmin Irani
    Malek Taher Maghsoodlou
    Nourallah Hazeri
    Journal of the Iranian Chemical Society, 2017, 14 : 1189 - 1193
  • [44] Synthesis, antioxidant and Aβ anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction
    Benchekroun, Mohamed
    Pachon-Angona, Irene
    Luzet, Vincent
    Martin, Helene
    Oset-Gasque, Maria-Jesus
    Marco-Contelles, Jose
    Ismaili, Lhassane
    BIOORGANIC CHEMISTRY, 2019, 85 : 221 - 228
  • [45] Efficient synthesis of new pyrano[2,3-d]pyrimidine-2,4-dione derivatives via a one-pot four-component reaction
    Irani, Sharmin
    Maghsoodlou, Malek Taher
    Hazeri, Nourallah
    JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2017, 14 (06) : 1189 - 1193
  • [46] Design and synthesis of benzylpyrazolyl coumarin derivatives via a four-component reaction in water: investigation of the weak interactions accumulating in the crystal structure of a signified compound
    Ghosh, Partha Pratim
    Pal, Gargi
    Paul, Sanjay
    Das, Asish R.
    GREEN CHEMISTRY, 2012, 14 (10) : 2691 - 2698
  • [47] One-pot synthesis of 4,5-dihydro-1H-pyrrol-3-carboxamide derivatives via a four-component reaction
    Alizadeh, Abdolah
    Rezvanian, Atieh
    Zhu, Long-Guan
    TETRAHEDRON, 2008, 64 (02) : 351 - 355
  • [48] Efficient Synthesis of Chromeno[4,3,2-de] [1,6]naphthyridine Derivatives via Pseudo Four-Component Reaction
    Gan, Jianbo
    Luo, Naili
    Wu, Chengjun
    Wan, Xinyi
    Wang, Cunde
    CHEMISTRYSELECT, 2021, 6 (34): : 9032 - 9037
  • [49] A one-pot procedure for the synthesis of novel pyran-fused dicyanoanilines via a triethylamine/aqueous mediated pseudo four-component reaction
    Abaee, M. Saeed
    Forghani, Soodabeh
    Mojtahedi, Mohammad M.
    Hadizadeh, Atefeh
    ARKIVOC, 2016, : 152 - 162
  • [50] Catalyst-free Synthesis of Tetrahydroacenaphtho[1,2-b]indolone Derivatives via One-pot Four-component Reaction
    Bayat, Mohammad
    Amiri, Zeinab
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (06) : 1346 - 1351