Synthesis of new indolylpyrrole derivatives via a four-component domino reaction between arylglyoxals, acetylacetone, indole and aliphatic amines in aqueous media

被引:11
|
作者
Mousavizadeh, Fereshteh [1 ]
Talebizadeh, Mahdiyeh [1 ]
Anary-Abbasinejad, Mohammad [1 ]
机构
[1] Vali e Asr Univ, Dept Chem, Rafsanjan 77176, Iran
关键词
Indolylpyrrole; Four-component reaction; Arylglyoxal; Aqueus media; Synthesis; MARTEFRAGIN;
D O I
10.1016/j.tetlet.2018.06.043
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel synthesis of indolylpyrrole derivatives is described by a four-component domino reaction between arylglyoxals, acetylacetone, indole and aliphatic amines in water as solvent at 60 degrees C without using any catalyst or promoter. The FT-IR, H-1 NMR, C-13 NMR spectral and elemental analysis confirm the structures of the products. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2970 / 2974
页数:5
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