To accurately model software failure process with software reliability growth models, incorporating testing effort has shown to be important. In fact, testing effort allocation is also a difficult issue, and it directly affects the software release time when a reliability criteria has to be met. However, with an increasing number of parameters involved in these models, the uncertainty of parameters estimated from the failure data could greatly affect the decision. Hence, it is of importance to study the impact of these model parameters. In this paper, sensitivity of the software release time is investigated through various methods, including one-factor-at-a-time approach, design of experiments and global sensitivity analysis. It is shown that the results from the first two methods may not be accurate enough for the case of complex nonlinear model. Global sensitivity analysis performs better due to the consideration of the global parameter space. The limitations of different approaches are also discussed. Finally, to avoid further excessive adjustment of software release time, interval estimation is recommended for use and it can be obtained based on the results from global sensitivity analysis. (c) 2010 Elsevier Inc. All rights reserved.