A facile synthesis of novel unsymmetrical N-(4-oxo-2-phenyl-3(4H)-quinazolinoyl)-N-(aryl)acetamidines

被引：3

作者：

Khan, Rasool ^{[1
]}

Arfan, Mohammad ^{[2
]}

Mahmood, Javeed ^{[2
]}

Anjum, Shazia ^{[3
]}

Choudhary, M. Iqbal ^{[4
]}

机构：

[1] Abdul Wali Khan Univ, Dept Chem, Mardan 23200, Nwfp, Pakistan

[2] Univ Peshawar, Inst Chem Sci, Peshawar 25120, Pakistan

[3] Univ Saskatchewan, Dept Chem, Saskatoon, SK S7N 5C9, Canada

[4] Univ Karachi, Int Ctr Chem & Biol Sci, HEJRIC, Karachi 75270, Pakistan

来源：

CHINESE CHEMICAL LETTERS | 2010年 / 21卷 / 08期

关键词：

3-Amino-2-phenyl-4(3H)-quinazolinone; Triethylorthoacetate; Unsymmetrical N-(4-oxo-2-phenyl-3(4H)-quinazolinoyl)-N-(aryl)acetamidines; AGENTS; QUINAZOLINONES; ACETAMIDINES;

D O I：

10.1016/j.cclet.2010.04.009

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of novel unsymmetrical N-(4-oxo-2-phenyl-3(4H)-quinazolinoyl)-N-(aryl)acetamidines was synthesized by reacting ethyl(1E)-N-(4-oxo-2-phenylquinazolin-3(4H)-yl)ethanimidoate (2) and suitable reactive aromatic amines. Structures' determination of the synthesized compounds was carried out using spectroscopic techniques including IR, (1)H NMR, and mass spectrometry. Structural effects on reactivity were also studied. (C) 2010 Rasool Khan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

引用

页码：905 / 910

页数：6

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