Synthesis of a phthalocyanine-1,4,6,10-tetraazaadamantane conjugate and its activity against the human immunodeficiency virus

被引：12
|
作者：
Tolbin, Alexander Yu. [1 ,2 ]
Sukhorukov, Alexey Yu. [3 ]
Ioffe, Sema L. [3 ]
Lobach, Olga A. [4 ]
Nosik, Dmitry N. [4 ]
Tomilova, Larisa G. [1 ,2 ]
机构：
[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia
[2] Russian Acad Sci, Inst Physiologically Act Cpds, Chernogolovka 142432, Moscow Region, Russia
[3] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow 119991, Russia
[4] Russian Acad Med Sci, DI Ivanovsky Inst Virol, Moscow 123098, Russia
来源：
MENDELEEV COMMUNICATIONS | 2010年 / 20卷 / 01期
基金：
俄罗斯基础研究基金会;
关键词：
PHTHALOCYANINE; PDT;
D O I：
10.1016/j.mencom.2010.01.010
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new type of phthalocyanine containing 3,5,7-trimethyl-1,4,6,10-tetraazatricyclo[3.3.1.1(3,7)]decane-4,6,10-trioI (1,4,6,10-tetraazaadamantane) within a peripheral substituent has been synthesised. Its spectral properties and interaction with human lymphoblastoma cells infected with the HIV-1(BRU) strain have been studied.
引用
收藏
页码：25 / 27
页数：3
相关论文
共 50 条
  • [21] SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF 6-SUBSTITUTED 2',3'-DIDEOXYPURINE NUCLEOSIDES AS POTENTIAL ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS AGENTS
    CHU, CK
    ULLAS, GV
    JEONG, LS
    AHN, SK
    DOBOSZEWSKI, B
    LIN, ZX
    BEACH, JW
    SCHINAZI, RF
    JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (06) : 1553 - 1561
  • [22] A new caffeoyl quinic acid from Aster scaber and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase
    Kwon, HC
    Jung, CM
    Shin, CG
    Lee, JK
    Choi, SU
    Kim, SY
    Lee, KR
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2000, 48 (11) : 1796 - 1798
  • [23] SYNTHESIS AND ANTIVIRAL ACTIVITY OF NEW 3,4-DIHYDRO-2-ALKOXY-6-BENZYL-4-OXOPYRIMIDINES (DABOS), SPECIFIC INHIBITORS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1
    MASSA, S
    MAI, A
    ARTICO, M
    SBARDELLA, G
    TRAMONTANO, E
    LOI, AG
    SCANO, P
    LACOLLA, P
    ANTIVIRAL CHEMISTRY & CHEMOTHERAPY, 1995, 6 (01): : 1 - 8
  • [24] SYNTHESIS AND ANTIVIRAL ACTIVITY OF VARIOUS 3'-AZIDO ANALOGS OF PYRIMIDINE DEOXYRIBONUCLEOSIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS (HIV-1, HTLV-III-LAV)
    LIN, TS
    GUO, JY
    SCHINAZI, RF
    CHU, CK
    XIANG, JN
    PRUSOFF, WH
    JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (02) : 336 - 340
  • [25] SYNTHESIS OF 1-(2-AMINOPROPYL)BENZIMIDAZOLES, STRUCTURALLY RELATED TO THE TIBO DERIVATIVE R82150, WITH ACTIVITY AGAINST HUMAN-IMMUNODEFICIENCY-VIRUS
    SWAYZE, EE
    PEIRIS, SM
    KUCERA, LS
    WHITE, EL
    WISE, DS
    DRACH, JC
    TOWNSEND, LB
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (04) : 543 - 546
  • [26] The Phthalocyanine Prototype Derivative Alcian Blue Is the First Synthetic Agent with Selective Anti-Human Immunodeficiency Virus Activity Due to Its gp120 Glycan-Binding Potential
    Francois, Katrien O.
    Pannecouque, Christophe
    Auwerx, Joeri
    Lozano, Virginia
    Perez-Perez, Maria-Jesus
    Schols, Dominique
    Balzarini, Jan
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (11) : 4852 - 4859
  • [27] Synthesis and antiviral activity of N-4'-dihydropyridinyl and dihydroquinolinylcarbonyl-2-hydroxymethyl-5-[cytosin-1'-yl]-1,3-oxathiolane derivatives against human immunodeficiency virus and duck hepatitis B virus
    Camplo, M
    CharvetFaury, AS
    Borel, C
    Turin, F
    Hantz, O
    Trabaud, C
    Niddam, V
    Mourier, N
    Graciet, JC
    Chermann, JC
    Kraus, JL
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1996, 31 (7-8) : 539 - 546
  • [28] A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase
    Kim, HJ
    Woo, ER
    Shin, CG
    Park, H
    JOURNAL OF NATURAL PRODUCTS, 1998, 61 (01): : 145 - 148
  • [29] Protecting-Group-Mediated Diastereoselective Synthesis of C4′-Methylated Uridine Analogs and Their Activity against the Human Respiratory Syncytial Virus
    Koellmann, Christoph
    Sake, Svenja M.
    Jones, Peter G.
    Pietschmann, Thomas
    Werz, Daniel B.
    JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (06): : 4267 - 4278
  • [30] Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors
    Dollé, V
    Nguyen, CH
    Legraverend, M
    Aubertin, AM
    Kirn, A
    Andreola, ML
    Ventura, M
    Tarrago-Litvak, L
    Bisagni, E
    JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (21) : 3949 - 3962
12345