A Bayesian Hierarchical Model for Classification with Selection of Functional Predictors

被引:39
|
作者
Zhu, Hongxiao [1 ]
Vannucci, Marina [2 ]
Cox, Dennis D. [2 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77230 USA
[2] Rice Univ, Dept Stat, Houston, TX 77005 USA
基金
美国国家科学基金会;
关键词
Bayesian hierarchical model; Evolutionary Monte Carlo; Functional data classification; Functional predictor selection; Fluorescence spectroscopy; MONTE-CARLO;
D O I
10.1111/j.1541-0420.2009.01283.x
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In functional data classification: functional observations are often contaminated by various systematic effects, such as random batch effects caused by device artifacts, or fixed effects caused by sample-related factors. These effects may lead to classification bias and thus should not be neglected. Another issue of concern is the selection of functions when predictors consist of multiple functions, smile of which may be redundant. The above issues arise in a real data application where we use fluorescence spectroscopy to detect cervical precancer. In this article, we propose a Bayesian hierarchical model that takes into account random batch effects and selects effective functions among multiple functional predictors. Fixed effects or predictors in nonfunctional form are also included in the model. The dimension of the functional data is reduced through orthonormal basis expansion or functional principal components. For posterior sampling, we use a hybrid Metropolis Hastings/Gibbs sampler. which suffers slow mixing. An evolutionary Monte Carlo algorithm is applied to improve the mixing. Simulation and real data application show that the proposed model provides accurate selection of functional predictors as well as good classification.
引用
收藏
页码:463 / 473
页数:11
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