In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents

被引：194
|
作者：
Almyroudis, Nikolaos G.
Sutton, Deanna A.
Fothergill, Annette W.
Rinaldi, Michael G.
Kusne, Shimon
机构：
[1] Roswell Pk Canc Inst, Dept Med, Buffalo, NY USA
[2] Dept Pathol, Fungus Testing Lab, San Antonio, TX USA
[3] Audie L Murphy Mem Vet Adm Med Ctr, S Texas Vet Hlth Care Syst, San Antonio, TX USA
[4] Mayo Clin, Phoenix, AZ USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 07期
关键词：
D O I：
10.1128/AAC.00452-07
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We evaluated the in vitro susceptibilities of 217 zygomycetes to amphotericin B, ketoconazole, fluconazole, itraconazole, voriconazole, posaconazole, caspofungin, and flucytosine. The significant in vitro activity of posaconazole against several species appears to support its reported clinical efficacy. Decreased susceptibility to amphotericin B was noted with Cunninghamella bertholletiae.
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页码：2587 / 2590
页数：4
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