Allele frequencies for 15 STR loci in Tibetan populations from Nepal

被引:20
|
作者
Ota, Masao
Droma, Yunden
Basnyat, Buddha
Katsuyama, Yoshihiko
Asamura, Hideki
Sakai, Hironori
Fukuhsima, Hirofumi
机构
[1] Shinshu Univ, Sch Med, Dept Legal Med, Matsumoto, Nagano 3908621, Japan
[2] Shinshu Univ, Sch Med, Dept Med, Matsumoto, Nagano 3908621, Japan
[3] Mt Med Soc Nepal, Nepal Int Clin, Kathmandu, Nepal
[4] Shinshu Univ Hosp, Dept Pharm, Matsumoto, Nagano 3908621, Japan
关键词
short tandem repeats (STRs); population data; AmpFLSTR (R) Identifiler (TM); Tibetan populations; Nepal;
D O I
10.1016/j.forsciint.2006.03.010
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Samples from 105 unrelated healthy Sherpa in Namehe Bazaar and I I I unrelated non-Sherpa in Kathmandu valley from Nepal were used to obtain allele frequency data for 15 short tandem repeat (STR) loci (CSFIPO, D2S1338, D3SI358, D5S818, D7S820, D8SI179, D13S317, D16S539, DISS51, D19S433, D21S11, FGA, TH01, TPOX and vWA) included in the AmpFLSTR (R) Identifiler (TM) kit. No deviations from Hardy-Weinberg equilibrium were observed, but only after applying a Bonferrom correction in the case of D5S818 in the Sherpa population and D7S820 in the Kathmandu population. Genetic parameters of forensic interest were calculated and genetic differentiation between the two populations tested. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:234 / 238
页数:5
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