Fe3O4/polyaniline nanoparticles with core-shell structure and their inductive heating property in AC magnetic field

被引:3
|
作者
Zhao, Dong-Lin [1 ]
Zeng, Xian-Wei [1 ]
Xia, Qi-Sheng [1 ]
Tang, Jin-Tian [1 ]
机构
[1] Beijing Univ Chem Technol, Syaye Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
关键词
Fe3O4/polyaniline nanoparticles; local hyperthermia; cancer treatment; biomedical applications;
D O I
10.4028/www.scientific.net/KEM.334-335.1189
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The magnetite (Fe3O4) nanoparticles were prepared by coprecipitation of Fe3+ and Fe2+ with aqueous NaOH solution. The Fe3O4/polyaniline (PANI) magnetic composite nanoparticles with core-shell structure with diameter of 30-50 nm were prepared via an in-situ polymerization of aniline in aqueous solution containing Fe3O4 magnetic fluid. The inductive heat property of Fe3O4/polyaniline composite nanoparticles in an alternating current (AC) magnetic field was investigated. The potential of Fe304/polyaniline nanoparticles was evaluated for localized hyperthermia treatment of cancers. The saturation magnetization Ms and coercivity He of Fe3O4 nanoparticles are 50.05 emu/g and 137 Oe respectively, the Fe3O4/polyaniline composite nanoparticles, 26.34 emu/g and 0 Oe. Exposed in the alternating current (AC) magnetic field for 29 min, the temperatures of physiological saline suspension containing Fe3O4 nanoparticles or Fe3O4/polyaniline composite nanoparticles are 63.6 degrees C and 52.4 degrees C respectively. The Fe3O4/polyaniline composite nanoparticles would be useful as good thermoseeds for localized hyperthermia treatment of cancers.
引用
收藏
页码:1189 / +
页数:2
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