Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells (vol 9, 250, 2018)

被引：4

作者：

Page, Brent D. G. ^{[1
]}

Valerie, Nicholas C. K. ^{[1
]}

Wright, Roni H. G. ^{[2
,3
]}

Wallner, Olov ^{[1
]}

Isaksson, Rebecka ^{[1
]}

Carter, Megan ^{[4
]}

Rudd, Sean G. ^{[1
]}

Loseva, Olga ^{[1
]}

Jemth, Ann-Sofie ^{[1
]}

Almlof, Ingrid ^{[1
]}

Font-Mateu, Jofre ^{[2
,3
]}

Llona-Minguez, Sabin ^{[1
]}

Baranczewski, Pawel ^{[5
]}

Jeppsson, Fredrik ^{[1
]}

Homan, Evert ^{[1
]}

Almqvist, Helena ^{[6
]}

Axelsson, Hanna ^{[6
]}

Regmi, Shruti ^{[6
]}

Gustavsson, Anna-Lena ^{[6
]}

Lundback, Thomas ^{[6
]}

Scobie, Martin ^{[1
]}

Stromberg, Kia ^{[1
]}

Stenmark, Pal ^{[4
]}

Beato, Miguel ^{[2
,3
]}

Helleday, Thomas ^{[1
]}

机构：

[1] Karolinska Inst, Dept Med Biochem & Biophys, Div Translat Med & Chem Biol, Sci Life Lab, SE-17121 Solna, Sweden

[2] Barcelona Inst Sci & Technol, CRG, E-09003 Barcelona, Spain

[3] Univ Pompeu Fabra, E-08003 Barcelona, Spain

[4] Stockholm Univ, Dept Biochem & Biophys, SE-10691 Stockholm, Sweden

[5] Uppsala Univ, Dept Pharm, Uppsala Univ Drug Optimizat & Pharmaceut Profilin, SE-75123 Uppsala, Sweden

[6] Karolinska Inst, Dept Med Biochem & Biophys, Div Translat Med & Chem Biol, Chem Biol Consortium Sweden,Sci Life Lab, SE-17121 Solna, Sweden

来源：

NATURE COMMUNICATIONS | 2019年 / 10卷 / 1期

基金：

欧洲研究理事会;

关键词：

D O I：

10.1038/s41467-019-12806-1

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

引用

页数：1

共 44 条

[1] Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Brent D. G. Page
Nicholas C. K. Valerie
Roni H. G. Wright
Olov Wallner
Rebecka Isaksson
Megan Carter
Sean G. Rudd
Olga Loseva
Ann-Sofie Jemth
Ingrid Almlöf
Jofre Font-Mateu
Sabin Llona-Minguez
Pawel Baranczewski
Fredrik Jeppsson
Evert Homan
Helena Almqvist
Hanna Axelsson
Shruti Regmi
Anna-Lena Gustavsson
Thomas Lundbäck
Martin Scobie
Kia Strömberg
Pål Stenmark
Miguel Beato
Thomas Helleday
Nature Communications, 9
[2] Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Page, Brent D. G.
Valerie, Nicholas C. K.
Wright, Roni H. G.
Wallner, Olov
Isaksson, Rebecka
Carter, Megan
Rudd, Sean G.
Loseva, Olga
Jemth, Ann-Sofie
Almlof, Ingrid
Font-Mateu, Jofre
Llona-Minguez, Sabin
Baranczewski, Pawel
Jeppsson, Fredrik
Homan, Evert
Almqvist, Helena
Axelsson, Hanna
Regmi, Shruti
Gustavsson, Anna-Lena
Lundback, Thomas
Scobie, Martin
Stromberg, Kia
Stenmark, Pal
Beato, Miguel
Helleday, Thomas
NATURE COMMUNICATIONS, 2018, 9
[3] Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Brent D. G. Page
Nicholas C. K. Valerie
Roni H. G. Wright
Olov Wallner
Rebecka Isaksson
Megan Carter
Sean G. Rudd
Olga Loseva
Ann-Sofie Jemth
Ingrid Almlöf
Jofre Font-Mateu
Sabin Llona-Minguez
Pawel Baranczewski
Fredrik Jeppsson
Evert Homan
Helena Almqvist
Hanna Axelsson
Shruti Regmi
Anna-Lena Gustavsson
Thomas Lundbäck
Martin Scobie
Kia Strömberg
Pål Stenmark
Miguel Beato
Thomas Helleday
Nature Communications, 10
[4] Targeted DNA repair in cancer and new NUDT5 inhibitors to block hormone signalling to target breast cancer
Helleday, T.
CANCER RESEARCH, 2020, 80 (04)
[5] Identification of promising inhibitors against breast cancer disease by targeting NUDIX hydrolase 5 (NUDT5) biomolecule
Almansour, Nahlah Makki
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2025, 43 (03): : 1171 - 1182
[6] The high expression of NUDT5 indicates poor prognosis of breast cancer by modulating AKT / Cyclin D signaling
Zhang, He
Zhang, Li-Qun
Yang, Cheng-Cheng
Li, Jin
Tian, Xin-Yuan
Li, Dan-Ni
Cui, Ju
Cai, Jian-Ping
PLOS ONE, 2021, 16 (02):
[7] Design of Novel Coumarin Derivatives as NUDT5 Antagonists That Act by Restricting ATP Synthesis in Breast Cancer Cells
Niranjan, Vidya
Jayaprasad, Sanjana
Uttarkar, Akshay
Kusanur, Raviraj
Kumar, Jitendra
MOLECULES, 2023, 28 (01):
[8] Design, molecular docking, and molecular dynamics of thiourea-iron (III) metal complexes as NUDT5 inhibitors for breast cancer treatment
Ruswanto, Ruswanto
Nofianti, Tita
Mardianingrum, Richa
Kesuma, Dini
Siswandono
HELIYON, 2022, 8 (09)
[9] Design, molecular docking, and molecular dynamics of thiourea-iron (III) metal complexes as NUDT5 inhibitors for breast cancer treatment (vol 8 e10694, 2022)
Ruswanto, Ruswanto
Nofianti, Tita
Mardianingrum, Richa
Kesuma, Dini
Siswandono
HELIYON, 2022, 8 (11)
[10] An efficient 2-aminothiazolesalicylaldehyde fluorescent chemosensor for Fe2+ ion detection and a potential inhibitor of NUDT5 signaling hormone for breast cancer cell and molecular keypad lock application
Basha, Summaya Banu
Charles, Immanuel David
Raju, Nandhakumar
Manokaran, Sakthivel
Kuzhandaivel, Hemalatha
CHEMICAL PAPERS, 2022, 76 (11) : 7061 - 7073

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