Clinical Trials of Pharmacological Therapies in Acute Heart Failure Syndromes Lessons Learned and Directions Forward

被引：116

作者：

Felker, G. Michael ^{[2
]}

Pang, Peter S. ^{[3
]}

Adams, Kirkwood F. ^{[4
,5
]}

Cleland, John G. F. ^{[6
]}

Cotter, Gad ^{[7
]}

Dickstein, Kenneth ^{[8
]}

Filippatos, Gerasimos S. ^{[9
]}

Fonarow, Gregg C. ^{[10
]}

Greenberg, Barry H. ^{[11
]}

Hernandez, Adrian F. ^{[12
]}

Khan, Sadiya

Komajda, Michel ^{[13
]}

Konstam, Marvin A. ^{[14
,15
]}

Liu, Peter P. ^{[16
]}

Maggioni, Aldo P. ^{[17
]}

Massie, Barry M. ^{[18
]}

McMurray, John J. ^{[19
]}

Mehra, Mandeep ^{[20
]}

Metra, Marco ^{[21
]}

O'Connell, John ^{[22
]}

O'Connor, Christopher M. ^{[23
]}

Pina, Ileana L. ^{[24
]}

Ponikowski, Piotr ^{[25
]}

Sabbah, Hani N. ^{[26
]}

Teerlink, John R. ^{[27
]}

Udelson, James E. ^{[28
]}

Yancy, Clyde W. ^{[29
]}

Zannad, Faiez ^{[30
]}

Gheorghiade, Mihai ^{[1
]}

机构：

[1] Northwestern Univ, Ctr Cardiovasc Qual & Outcomes, Feinberg Sch Med, Dept Med, 645 N Michigan Ave,Suite 1006, Chicago, IL 60611 USA

[2] Duke Clin Res Inst Durham, Durham, NC USA

[3] Northwestern Univ, Ctr Cardiovasc Qual & Outcomes, Feinberg Sch Med, Dept Emergency Med, Chicago, IL 60611 USA

[4] Univ N Carolina, Sch Med, Dept Med, Chapel Hill, NC USA

[5] Univ N Carolina, Sch Med, Dept Radiol, Chapel Hill, NC 27514 USA

[6] Univ Hull, Dept Cardiol, Castle Hill Hosp, Kingston Upon Hull, Yorks, England

[7] Momentum Res Inc, Durham, NC USA

[8] Univ Bergen, Inst Internal Med, Bergen, Norway

[9] Univ Athens, Hosp Attikon, Athens, Greece

[10] David Geffen UCLA, Med Ctr, Ahmanson UCLA Cardiomyopathy Ctr, Los Angeles, CA USA

[11] Univ Calif San Diego, San Diego, CA 92103 USA

[12] Duke Univ, Sch Med, Duke Clin Res Inst, Durham, NC USA

[13] Univ Paris 06, AP HP, Paris, France

[14] Tufts Med Ctr, Ctr Cardiovasc, Boston, MA USA

[15] Tufts Univ, Sch Med, Boston, MA 02111 USA

[16] Univ Toronto, Toronto Gen Hosp, Inst Circulatory & Resp Hlth, Canadian Inst Hlth, Toronto, ON M5S 1A1, Canada

[17] ANMCO Res Ctr, Florence, Italy

[18] Univ Calif San Francisco, Div Cardiol, San Francisco Vet Affairs Med Ctr, San Francisco, CA 94143 USA

[19] Univ Glasgow, BHF Cardiovasc Res Ctr, Glasgow, Lanark, Scotland

[20] Univ Maryland, Sch Med, Baltimore, MD 21201 USA

[21] Univ & Civil Hosp Brescia, Dept Expt & Appl Med, Brescia, Italy

[22] Feinberg Sch Med, Div Cardiol, Chicago, IL USA

[23] Duke Univ, Med Ctr, Duke Heart Ctr, Div Clin Pharmacol, Durham, NC 27710 USA

[24] Case Western Reserve Univ, Cleveland, OH 44106 USA

[25] Med Univ, Fac Hlth Sci, Clin Mil Hosp, Wroclaw, Poland

[26] Henry Ford Hosp, Dept Med, Detroit, MI 48202 USA

[27] Vet Affairs Med Ctr, San Francisco, CA 94121 USA

[28] Tufts Med Ctr, Div Cardiol, Boston, MA USA

[29] Baylor Heart & Vasc Inst, Dallas, TX USA

[30] Nancy Univ, Dept Cardiol, Nancy, France

来源：

CIRCULATION-HEART FAILURE | 2010年 / 3卷 / 02期

关键词：

heart failure; patients; trials; acute heart failure; WORSENING RENAL-FUNCTION; IN-HOSPITAL MORTALITY; RANDOMIZED CONTROLLED-TRIALS; CARDIAC TROPONIN-I; END-POINTS; MYOCARDIAL-INFARCTION; RISK STRATIFICATION; FLUID ACCUMULATION; PROGNOSTIC VALUE; OUTCOMES;

D O I：

10.1161/CIRCHEARTFAILURE.109.893222

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：314 / 325

页数：12

共 50 条

[31] Genome-wide studies of heart failure and endophenotypes: lessons learned and future directions
van der Ende, Maaike Yldau
Said, Mir Abdullah
van Veldhuisen, Dirk Jan
Verweij, Niek
van der Harst, Pim
CARDIOVASCULAR RESEARCH, 2018, 114 (09) : 1209 - 1225
[32] Lessons Learned: Clinical Trials and Operations
Evans, S.
MEDICAL PHYSICS, 2016, 43 (06) : 3790 - 3790
[33] Lessons from Epidemiological Study of Acute Heart Failure Syndromes in Japan
Sato, Naoki
Mizuno, Kyoichi
JOURNAL OF CARDIAC FAILURE, 2012, 18 (10) : S127 - S127
[34] Acute renal failure: Controversies, clinical trials, and future directions
Paller, MS
SEMINARS IN NEPHROLOGY, 1998, 18 (05) : 482 - 489
[35] Lessons learned from the Walking Forward Program in recruiting American Indians on clinical trials
Peterelt, Daniel G.
Kanekar, Shalini
Guadanolo, Ashleigh
Boylan, Amy
Cina, Kristin
Burhansstipanov, Linda
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2014, 23 (11)
[36] A proposal to standardize dyspnoea measurement in clinical trials of acute heart failure syndromes: the need for a uniform approach
Pang, Peter S.
Cleland, John G. F.
Teerlink, John R.
Collins, Sean P.
Lindsell, Christopher J.
Sopko, George
Peacock, W. Frank
Fonarow, Gregg C.
Aldeen, Amer Z.
Kirk, J. Douglas
Storrow, Alan B.
Tavares, Miguel
Mebazaa, Alexandre
Roland, Edmond
Massie, Barry M.
Maisel, Alan S.
Komajda, Michel
Filippatos, Gerasimos
Gheorghiade, Mihai
EUROPEAN HEART JOURNAL, 2008, 29 (06) : 816 - 824
[37] Pharmacological options for acute heart failure syndromes: current treatments and unmet needs
Nieminen, MS
EUROPEAN HEART JOURNAL SUPPLEMENTS, 2005, 7 (0B) : B20 - B24
[38] Acute Heart Failure Syndromes
Gheorghiade, Mihai
Pang, Peter S.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 53 (07) : 557 - 573
[39] Platelet glycoprotein IIb/IIIa antagonists: Lessons learned from clinical trials and future directions
Leclerc, JR
CRITICAL CARE MEDICINE, 2002, 30 (05) : S332 - S340
[40] Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions
Andrieu, Sandrine
Coley, Nicola
Lovestone, Simon
Aisen, Paul S.
Vellas, Bruno
LANCET NEUROLOGY, 2015, 14 (09): : 926 - 944

← 1 2 3 4 5 →