Corneal neurotisation by great auricular nerve transfer and scleral-corneal tunnel incisions for neurotrophic keratopathy
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作者:
Jowett, Nate
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Massachusetts Eye & Ear Infirm, Dept Otolaryngol, 243 Charles St, Boston, MA 02114 USA
Harvard Med Sch, Boston, MA 02114 USAMassachusetts Eye & Ear Infirm, Dept Otolaryngol, 243 Charles St, Boston, MA 02114 USA
Jowett, Nate
[1
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Pineda, Roberto, II
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机构:Massachusetts Eye & Ear Infirm, Dept Otolaryngol, 243 Charles St, Boston, MA 02114 USA
Pineda, Roberto, II
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[1] Massachusetts Eye & Ear Infirm, Dept Otolaryngol, 243 Charles St, Boston, MA 02114 USA
Background/Aims Medical management of neurotrophickeratopathy is challenging and costly. Supra-orbital nerve transfer to thecornea has proven effective for management of keratopathy, but yieldsconsiderable donor site morbidity. Herein, a novel technique for reinnervationof the anaesthetic cornea is presented and early results characterised. Methods Sensory fibres of the ipsilateral greatauricular nerve were directed via an interposition graft to the anteriorcorneal stroma using scleral-corneal tunnel incisions in two patients withgrade III neurotrophic keratopathy. Results Improvements in visual acuity, cornealpachymetry, corneal esthesiometry, and corneal neurotisation as assessed by invivo confocal microscopy were observed within nine months of surgery in bothpatients. Conclusion Corneal neurotisation by interposition grafttransfer of great auricular nerve fibres via scleral-corneal tunnel incisionsappears effective in the management of neurotrophic keratopathy.
机构:
Moorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, EnglandMoorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, England
Lau, Nicola
Osborne, Sarah F.
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Moorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, EnglandMoorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, England
Osborne, Sarah F.
Vasquez-Perez, Alfonso
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Moorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, EnglandMoorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, England
Vasquez-Perez, Alfonso
Wilde, Caroline L.
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Moorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, EnglandMoorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, England
Wilde, Caroline L.
Manisali, Mehmet
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St Georges Hosp NHS Fdn Trust, Dept Maxillofacial Surg, London, EnglandMoorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, England
Manisali, Mehmet
Jayaram, Rahul
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St Georges Hosp NHS Fdn Trust, Dept Maxillofacial Surg, London, EnglandMoorfields Eye Hosp NHS Fdn Trust, Dept Ophthalmol, St Georges Hosp, Blackshaw Rd, London SW17 0QT, England
机构:
Indiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USA
Indiana Univ Sch Med, 340 10th St, Indianapolis, IN 46202 USAIndiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USA
Gross, Jeffrey N.
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Bhagat, Neel
Tran, Khoa
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Indiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USAIndiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USA
Tran, Khoa
Liu, Shaohui
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Indiana Univ Sch Med, Dept Ophthalmol, Indianapolis, IN USAIndiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USA
Liu, Shaohui
Boente, Charline S.
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Indiana Univ Sch Med, Dept Ophthalmol, Indianapolis, IN USAIndiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USA
Boente, Charline S.
Ali, Asim
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Hosp Sick Children, Dept Ophthalmol & Vis Sci, Toronto, ON, CanadaIndiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USA
Ali, Asim
Borschel, Gregory H.
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Indiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USA
Indiana Univ Sch Med, Dept Ophthalmol, Indianapolis, IN USAIndiana Univ Sch Med, Div Plast Surg, Indianapolis, IN USA