Aromatic compounds from the sclerotia of Inonotus obliquus

被引：4

作者：

Zou, Chun-xin ^{[1
,2
]}

Zhang, Yang-Yang ^{[1
]}

Bai, Ming ^{[1
]}

Huang, Xiao-Xiao ^{[1
,2
]}

Wang, Xiao-Bo ^{[1
,2
]}

Song, Shao-Jiang ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Key Lab Computat Chem Nat Antitumor Drug Res & De, Shenyang, Peoples R China

[2] Chinese Peoples Liberat Army Logist Support Forc, Dalian, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2021年 / 35卷 / 14期

关键词：

Inonotus obliquus; aromatic compounds; ECD calculation; cytotoxicity; LANOSTANE-TYPE TRITERPENOIDS; ETHANOL EXTRACT; ANTITUMOR;

D O I：

10.1080/14786419.2019.1677656

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Three new aromatic compounds (1a/1b, 2) including a pair of enantiomers (1a/1b), were isolated from Inonotus obliquus. The structures of the new compounds were elucidated by extensive spectroscopic analyses, and the absolute configurations of 1a and 1b were determined by electronic circular dichroism (ECD) calculated. All isolates were evaluated for their cytotoxic activities against Hep3B and HepG2 cell lines. Compounds 1b and 2 showed weak cytotoxicity toward the Hep3B cells at 25??M.

引用

页码：2454 / 2457

页数：4

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