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Chinese Acad Med Sci & Peking Union Med Coll, Dept Rheumatol, Peking Union Med Coll Hosp, Natl Clin Res Ctr Dermatol & Immunol Dis NCRC DID, 1 Shuai Fu Yuan,Wangfujing St, Beijing 100730, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Dept Rheumatol, Peking Union Med Coll Hosp, Natl Clin Res Ctr Dermatol & Immunol Dis NCRC DID, 1 Shuai Fu Yuan,Wangfujing St, Beijing 100730, Peoples R China