Quality of Life in Early Breast Cancer Patients: A Prospective Observational Study Using the FACT-B Questionnaire

被引：7
|
作者：
Ursini, Lucia Anna [1 ]
Nuzzo, Marianna [1 ]
Rosa, Consuelo [1 ,2 ]
Di Guglielmo, Fiorella Cristina [1 ]
Di Tommaso, Monica [1 ]
Trignani, Marianna [1 ]
Borgia, Marzia [1 ]
Allajbej, Albina [1 ]
Patani, Fabiola [1 ]
Di Carlo, Clelia [1 ]
Porreca, Annamaria [3 ]
Di Nicola, Marta [4 ]
Genovesi, Domenico [1 ,2 ]
Caravatta, Luciana [1 ]
机构：
[1] Univ G dAnnunzio, SS Annunziata Hosp, Dept Radiat Oncol, Via Dei Vestini, I-66100 Chieti, Italy
[2] Univ G dAnnunzio, Dept Neurosci Imaging & Clin Sci, Chieti, Italy
[3] G Annunzio Univ Chieti Pescara, Dept Econ, Pescara, Italy
[4] Univ G dAnnunzio, Dept Med Oral & Biotechnol Sci, Lab Biostat, Chieti, Italy
来源：
IN VIVO | 2021年 / 35卷 / 03期
关键词：
Early breast cancer; hormone therapy; hypofractionation; quality of life; radiation therapy; RANDOMIZED CONTROLLED-TRIAL; FUNCTIONAL ASSESSMENT; CONSERVING SURGERY; THERAPY; WOMEN; VALIDATION; MASTECTOMY; TOXICITY; OUTCOMES; IMPACT;
D O I：
10.21873/invivo.12443
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Background/Aim: Quality of life (QoL) in early breast cancer (BC) treatment may be affected by acute and late toxicities. This study evaluated the impact of radiotherapy (RT) schedules, treatment-related toxicities, hormone therapy (HT) and age on QoL. Patients and Methods: Ninety-five patients answered the FACT-B 4.0 questionnaire. Acute or late toxicities were recorded at each follow-up visit. Results: The median trend of the QoL subscales was stable during all questionnaires. HT negatively impacted on Functional Assessment of Cancer Therapy General-Total, functional and emotional wellbeing. No difference was recorded between RT schedules and toxicity. No significant differences for age were detected in QoL. Conclusion: RT seems not to influence QoL of BC patients, in terms of fractionation regimen or RT-related side-effects. Moreover, women having systemic HT experienced a QoL worse than patients treated with RT only. Further and longterm protocols are needed to improve the validity of the tool.
引用
收藏
页码：1821 / 1828
页数：8
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