ESAS and FACT-B in eribulin-treated metastatic breast cancer patients: a multicenter, prospective and observational study

被引：3

作者：

Moscetti, Luca ^{[1
,7
]}

Mentuccia, Lucia ^{[2
]}

Vici, Patrizia ^{[3
]}

Quadrini, Silvia ^{[2
]}

Sperduti, Isabella ^{[4
]}

Pizzuti, Laura ^{[3
]}

Fabbri, Maria Agnese ^{[1
]}

Vaccaro, Angela ^{[2
]}

Sacca, Marcello Maugeri ^{[3
,6
]}

Barba, Maddalena ^{[3
,6
]}

Sergi, Domenico ^{[3
]}

Zampa, Germano ^{[5
]}

Gamucci, Teresa ^{[2
]}

机构：

[1] Belcolle Hosp, AUSL Viterbo, Div Med Oncol, Viterbo, Italy

[2] ASL Frosinone, Med Oncol Unit, Frosinone, Italy

[3] Regina Elena Inst Canc Res, Div Med Oncol B, Rome, Italy

[4] Regina Elena Inst Canc Res, Biostat, Rome, Italy

[5] Nuovo Regina Margherita Hosp, Med Oncol Unit, Rome, Italy

[6] Regina Elena Inst Canc Res, Sci Direct, Rome, Italy

[7] Azienda Osped Univ Policlin Modena, Dept Oncol & Hematol, Modena, Italy

来源：

FUTURE ONCOLOGY | 2017年 / 13卷 / 17期

关键词：

Edmonton symptoms assessment scale; eribulin mesylate; metastatic breast cancer; quality of life; QUALITY-OF-LIFE; CAPECITABINE; MESYLATE; SCALE;

D O I：

10.2217/fon-2017-0062

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aim: Quality of life (QoL) is a critical issue for women with metastatic breast cancer (MBC). Eribulin mesylate represents a novel and active drug for pretreated MBC. Regretfully, few data exploring health-related (HR) QoL are available in unselected populations. Patients & methods: A multicenter prospective observational study was conducted in 50 MBC patients treated with eribulin mesylate, in order to evaluate HRQoL and patients' well-being by using the Edmonton symptoms assessment scale (ESAS) and Functional Assessment of Cancer Therapy-Breast questionnaires. Results: A significant ESAS score improvement was observed with a 10% median decrease. No differences were revealed for the QoL scores. Conclusion: The analysis of ESAS and Functional Assessment of Cancer Therapy scores showed that eribulin mesylate contributes to preserve QoL in MBC patients.

引用

页码：1517 / 1525

页数：9

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