CHEMICAL CONSTITUENTS AND LIPOXYGENASE INHIBITORY ACTIVITY OF PIPER STYLOSUM MIQ.

被引:16
|
作者
Salleh, Wan Mohd Nuzul Hakimi Wan [1 ]
Hashim, Nur Athirah [2 ]
Khamis, Shamsul [3 ]
机构
[1] Univ Pendidikan Sultan Idris, Fac Sci & Math, Dept Chem, Tanjung Malim 35900, Perak, Malaysia
[2] Univ Teknol Malaysia, Fac Sci, Dept Chem, Skudai 81310, Johor, Malaysia
[3] Univ Kebangsaan Malaysia, Fac Sci & Technol, Sch Environm & Nat Sci, Bangi 43600, Selangor, Malaysia
关键词
Piperaceae; Piper; Piper stylosum; Lignan; Lipoxygenase; ESSENTIAL OILS; NEOLIGNANS; ANTIOXIDANT; EXTRACTS; FRUITS; LIGNAN;
D O I
10.4314/bcse.v33i3.19
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chemical constituents and lipoxygenase inhibitory activity of the aerial part of Piper stylosum have been studied. Fractionation and purification of the extracts afforded five lignans, identified as yangambin (1), sesamin (2), syringaresinol (3), pinoresinol (4), and medioresinol (5), together with other constituents; 4-allyl resorcinol, beta-sitosterol, beta-sitostenone, taraxerol, vanilin, and vanilic acid. The structures of these compounds were established by analysis of their spectral data, as compared to that of reported compounds. The lipoxygenase inhibitory activity of the extracts and isolated lignans were also evaluated.
引用
收藏
页码:587 / 592
页数:6
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