Synthesis and properties of 4,5-trans-4-aryl-3-cyano-6-hydroxy-6-methyl-5-pyridinio-1,4,5,6-tetrahydropyridine-2-thiolates

被引：0

作者：

Krauze, A ^{[1
]}

Duburs, G ^{[1
]}

机构：

[1] Latvian Inst Organ Synth, LV-1006 Riga, Latvia

来源：

HETEROCYCLIC COMMUNICATIONS | 2000年 / 6卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4,5-trans-4-Aryl-3-cyano-6-hydroxy-6-methyl-5-pyridinio-1,4, 5, 6-tetrahydropyridine-2-thiolates 4 were obtained by cyclocondensation of 1-acetonylpyridinium chloride (1) under bar, aromatic aldehyde (2) under bar and cyanothioacetamide (3) under bar. 6-Hydroxy-6-methyl-4-phenyl-5-pyridiniohexahydropyridine-2-thione chlorides (5) under bar occurring as a mixture of thione and enethiol tautomers, were prepared by treatment of thiolate <(4a)under bar> with hydrochloric acid. Dehydration and dehydrogenation of thiolates (4) under bar have been carried out as well. Steric structures of hydrogenated 6-hydroxypyridines (4) under bar, (5) under bar are discussed in the light of NMR spectra.

引用

页码：265 / 270

页数：6

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