Exploring new transcranial electrical stimulation strategies to modulate brain function in animal models

被引:6
|
作者
Sanchez-Leon, Carlos A. [1 ]
Sanchez-Lopez, Alvaro [1 ]
Ammann, Claudia [2 ]
Cordones, Isabel [1 ]
Carretero-Guillen, Alejandro [1 ]
Marquez-Ruiz, Javier [1 ]
机构
[1] Pablo Olavide Univ, Dept Physiol Anat & Cell Biol, Seville 41013, Spain
[2] CEU San Pablo Univ, Univ Hosp HM Puerta, CINAC, Mostoles 28938, Spain
基金
美国国家卫生研究院;
关键词
Transcranial electrical stimulation; tDCS; tACS; tRNS; Neuromodulation; Animal models;
D O I
10.1016/j.cobme.2018.09.001
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Transcranial electrical stimulation (tES) refers to a group of non-invasive brain stimulation techniques to induce changes in the excitability of cortical neurons in humans. In recent years, studies in animal models have been shown to be essential for disentangling the neuromodulatory effects of tES, defining safety limits, and exploring potential therapeutic applications in neurological and neuropsychiatric disorders. Testing in animal models is valuable for the development of new unconventional protocols intended to improve tES administration and optimize the desired effects by increasing its focality and enabling deep-brain stimulation. Successful and controlled application of tES in humans relies on the knowledge acquired from studies meticulously performed in animal models.
引用
收藏
页码:7 / 13
页数:7
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