cAMP and Ca2+ interplay:: a matter of oscillation patterns

被引:62
|
作者
Zaccolo, M
Pozzan, T
机构
[1] Venetian Inst Mol Med, Dulbecco Telethon Inst, Padua, Italy
[2] Univ Padua, Dept Biomed Sci, Venetian Inst Mol Med, Padua, Italy
关键词
D O I
10.1016/S0166-2236(02)00017-6
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Ca2+ and cAMP signalling pathways are tightly interconnected and the cellular effects mediated by the two second messengers depend strictly on reciprocal modulation. The signalling network that derives from such interplay holds the potential for expanding the information content of the signal enormously and, thus, can contribute substantially to the specificity and diversity of the response. Recent work points to interdependent Ca2+ and cAMP oscillation patterns as a new paradigm for signal transduction.
引用
收藏
页码:53 / 55
页数:3
相关论文
共 50 条
  • [1] Oscillation of cAMP and Ca2+ in cardiac myocytes: a systems biology approach
    Kamide, Takehisa
    Okumura, Satoshi
    Ghosh, Samik
    Shinoda, Yoko
    Mototani, Yasumasa
    Ohnuki, Yoshiki
    Jin, Huiling
    Cai, Wenqian
    Suita, Kenji
    Sato, Itaru
    Umemura, Masanari
    Fujita, Takayuki
    Yokoyama, Utako
    Sato, Motohiko
    Furutani, Kazuharu
    Kitano, Hiroaki
    Ishikawa, Yoshihiro
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 2015, 65 (02): : 195 - 200
  • [2] Oscillation of cAMP and Ca2+ in cardiac myocytes: a systems biology approach
    Takehisa Kamide
    Satoshi Okumura
    Samik Ghosh
    Yoko Shinoda
    Yasumasa Mototani
    Yoshiki Ohnuki
    Huiling Jin
    Wenqian Cai
    Kenji Suita
    Itaru Sato
    Masanari Umemura
    Takayuki Fujita
    Utako Yokoyama
    Motohiko Sato
    Kazuharu Furutani
    Hiroaki Kitano
    Yoshihiro Ishikawa
    The Journal of Physiological Sciences, 2015, 65 : 195 - 200
  • [3] The Interplay Between Asthma and Other Diseases: Role of Ca2+/cAMP Signalling
    Bergantin, Leandro B.
    ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2020, 20 (03) : 321 - 327
  • [4] Compartmentalisation of cAMP and Ca2+ signals
    Zaccolo, M
    Magalhaes, P
    Pozzan, T
    CURRENT OPINION IN CELL BIOLOGY, 2002, 14 (02) : 160 - 166
  • [5] Interplay among cGMP, cAMP, and Ca2+ in Living Olfactory Sensory Neurons In Vitro and In Vivo
    Pietrobon, Mara
    Zamparo, Ilaria
    Maritan, Micol
    Franchi, Sira Angela
    Pozzan, Tullio
    Lodovichi, Claudia
    JOURNAL OF NEUROSCIENCE, 2011, 31 (23): : 8395 - 8405
  • [6] Phosphoinositide metabolism and Ca2+ oscillation
    Tkachuk, VA
    BIOCHEMISTRY-MOSCOW, 1998, 63 (01) : 38 - 46
  • [7] Synchronization of Ca2+ oscillation by fluctuations in the membrane potential of Ca2+ stores
    Yamashita, Masayuki
    NEUROSCIENCE RESEARCH, 2008, 61 : S88 - S88
  • [8] Ca2+ entry modulates oscillation frequency by triggering Ca2+ release
    Shuttleworth, TJ
    Thompson, JL
    BIOCHEMICAL JOURNAL, 1996, 313 : 815 - 819
  • [9] Spatial Ca2+ profiling: decrypting the universal cytosolic Ca2+ oscillation
    Samanta, Krishna
    Parekh, Anant B.
    JOURNAL OF PHYSIOLOGY-LONDON, 2017, 595 (10): : 3053 - 3062
  • [10] Wound Repair and Ca2+ Signalling Interplay: The Role of Ca2+ Channels in Skin
    Bonsignore, Gregorio
    Martinotti, Simona
    Ranzato, Elia
    CELLS, 2024, 13 (06)