Screening breast cancer patients for Norwegian ATM mutations

被引：9

作者：

Laake, K

Vu, P

Andersen, TI

Erikstein, B

Kåresen, R

Lonning, PE

Skovlund, E

Borresen-Dale, AL ^{[1
]}

机构：

[1] Norwegian Radium Hosp, Dept Genet, N-0310 Oslo, Norway

[2] Univ Oslo, Ulleval Hosp, Dept Oncol, N-0407 Oslo, Norway

[3] Univ Oslo, Ulleval Hosp, Dept Surg, N-0407 Oslo, Norway

[4] Norwegian Radium Hosp, Dept Oncol, N-0310 Oslo, Norway

[5] Norwegian Radium Hosp, Clin Res Off, N-0310 Oslo, Norway

[6] Haukeland Hosp, Dept Oncol, N-5021 Bergen, Norway

来源：

BRITISH JOURNAL OF CANCER | 2000年 / 83卷 / 12期

关键词：

ataxia telangiectasia; breast neoplasms; heterozygote detection; polymerase chain reaction; breast cancer risk; Norwegian founder mutation;

D O I：

10.1054/bjoc.2000.1519

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

483 Norwegian breast cancer patients were screened for six different ataxia telangiectasia mutated (ATM) mutations previously found to account for 83% of the disease alleles in Norwegian ataxia telangiectasia (AT) patients. Only one carrier was found. These results provide no evidence in favour of an excess risk of breast cancer associated with heterozygosity for classical AT mutations, but remain consistent with a maximum 2.4-fold increased risk. (C) 2000 Cancer Research Campaign.

引用

页码：1650 / 1653

页数：4

共 50 条

[21] Breast cancer mortality in participants of the Norwegian Breast Cancer Screening Program
Hofvind, Solveig
Ursin, Giske
Tretli, Steinar
Sebuodegard, Sofie
Moller, Bjorn
CANCER, 2013, 119 (17) : 3106 - 3112
[22] Overdiagnosis of breast cancer in the Norwegian Breast Cancer Screening Program estimated by the Norwegian Women and Cancer cohort study
Eiliv Lund
Nicolle Mode
Marit Waaseth
Jean-Christophe Thalabard
BMC Cancer, 13
[23] Overdiagnosis of breast cancer in the Norwegian Breast Cancer Screening Program estimated by the Norwegian Women and Cancer cohort study
Lund, Eiliv
Mode, Nicolle
Waaseth, Marit
Thalabard, Jean-Christophe
BMC CANCER, 2013, 13
[24] Contributions of ATM mutations to familial breast and ovarian cancer
Thorstenson, YR
Roxas, A
Kroiss, R
Jenkins, MA
Yu, KM
Bachrich, T
Muhr, D
Wayne, TL
Chu, G
Davis, RW
Wagner, TMU
Oefner, PJ
CANCER RESEARCH, 2003, 63 (12) : 3325 - 3333
[25] Dominant negative ATM mutations in breast cancer families
Chenevix-Trench, G
Spurdle, AB
Gatei, M
Kelly, H
Marsh, A
Chen, XQ
Donn, K
Cummings, M
Nyholt, D
Jenkins, MA
Scott, C
Pupo, GM
Dörk, T
Bendix, R
Kirk, J
Tucker, K
McCredie, MRE
Hopper, JL
Sambrook, J
Mann, GJ
Khanna, KK
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2002, 94 (03): : 205 - 215
[26] ATM mutations in breast cancer patients with early-onset or family history.
Teraoka, SN
Malone, KE
Ostrander, EA
Daling, JR
Concannon, P
AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 65 (04) : A326 - A326
[27] Multi-center screening of mutations in the ATM gene among women with breast cancer - The WECARE study
Bernstein, JL
Concannon, P
Langholz, B
Thompson, WD
Bernstein, L
Stovall, M
Thomas, DC
RADIATION RESEARCH, 2005, 163 (06) : 698 - 699
[28] ATM Mutations in Patients with Hereditary Pancreatic Cancer
Roberts, Nicholas J.
Jiao, Yuchen
Yu, Jun
Kopelovich, Levy
Petersen, Gloria M.
Bondy, Melissa L.
Gallinger, Steven
Schwartz, Ann G.
Syngal, Sapna
Cote, Michele L.
Axilbund, Jennifer
Schulick, Richard
Ali, Syed Z.
Eshleman, James R.
Velculescu, Victor E.
Goggins, Michael
Vogelstein, Bert
Papadopoulos, Nickolas
Hruban, Ralph H.
Kinzler, Kenneth W.
Klein, Alison P.
CANCER DISCOVERY, 2012, 2 (01) : 41 - 46
[29] Re: Dominant negative ATM mutations in breast cancer families
Lei, HX
Pospisilova, D
Lindblom, A
Vorechovsky, I
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2002, 94 (12) : 951 - 952
[30] Contribution of mutations in ATM to breast cancer development in the Czech population
Soukupova, Jana
Dundr, Pavel
Kleibl, Zdenek
Pohlreich, Petr
ONCOLOGY REPORTS, 2008, 19 (06) : 1505 - 1510

← 1 2 3 4 5 →