Objectives Salivary ultrasonography (US) was evaluated as an alternative imaging modality to sialography for Sjogren's syndrome (SS). Methods Parotid sialography and parotid and submandibular US were performed in 360 patients (188 with SS and 172 non-SS) who were suspected of SS and had fulfilled the American-European criteria (AEC) for SS or had received >= 3 of the objective examinations that were considered minimal requirements for classifying non-SS and had undergone both the imaging examinations. The glands were considered positive for SS if they exhibited peripheral sialoectatic changes on sialography and/or hypoechoic areas, echogenic streaks and/or irregular gland margins on US. The images obtained were independently rated as SS-positive or SS-negative by three radiologists in a blind fashion and the final decision was made by consensus. Interobserver and intermodality agreement was evaluated using. values for sialography and parotid and/or submandibular US. Results Average. values for the interobserver agreement were 0.81, 0.80 and 0.82 in sialography, parotid and submandibular US, respectively, indicating very good or good agreement. The. value for intermodality agreement between sialography and parotid US was 0.81 and between sialography and submandibular US was 0.76, indicating very good and good agreement, respectively. The diagnostic ability of parotid US was significantly lower than that of sialography (p<0.001, McNemar test). However, the diagnostic ability of submandibular US was comparable to that of sialography (p=0.153). Conclusions Submandibular US is a promising technique that can be used as a practical alternative to sialography in the classification of SS.
机构:
Konkuk Univ, Dept Nucl Med, Seoul, South KoreaKonkuk Univ, Med Ctr, Dept Internal Med, Div Rheumatol, Seoul, South Korea
Jo, Joon-Hyung
So, Young
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Konkuk Univ, Dept Nucl Med, Seoul, South KoreaKonkuk Univ, Med Ctr, Dept Internal Med, Div Rheumatol, Seoul, South Korea
So, Young
Chung, Hyun Woo
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Konkuk Univ, Dept Nucl Med, Seoul, South KoreaKonkuk Univ, Med Ctr, Dept Internal Med, Div Rheumatol, Seoul, South Korea
Chung, Hyun Woo
Lee, Sang-Heon
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Konkuk Univ, Med Ctr, Sch Med, Div Rheumatol,Dept Internal Med,Res Inst Med Sci, Seoul, South KoreaKonkuk Univ, Med Ctr, Dept Internal Med, Div Rheumatol, Seoul, South Korea
Lee, Sang-Heon
Kim, Hae-Rim
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Konkuk Univ, Med Ctr, Sch Med, Div Rheumatol,Dept Internal Med,Res Inst Med Sci, Seoul, South KoreaKonkuk Univ, Med Ctr, Dept Internal Med, Div Rheumatol, Seoul, South Korea
机构:
Kyung Hee Univ, Coll Med, Kyung Hee Univ Hosp Gangdong, Div Rheumatol,Dept Internal Med, Seoul, South KoreaKyung Hee Univ, Coll Med, Kyung Hee Univ Hosp Gangdong, Div Rheumatol,Dept Internal Med, Seoul, South Korea
Kim, Se Hee
Min, Hong Ki
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Konkuk Univ, Res Inst Med Sci, Dept Internal Med, Div Rheumatol,Sch Med, 120-1 Neungdong Ro Hwayang Dong, Seoul 143729, South KoreaKyung Hee Univ, Coll Med, Kyung Hee Univ Hosp Gangdong, Div Rheumatol,Dept Internal Med, Seoul, South Korea
机构:
Hadassah Hebrew Univ, Med Ctr, Dept Oral Med Sedat & Maxillofacial Imaging, Jerusalem, Israel
Hadassah Hebrew Univ, Med Ctr, Siogrens Syndrome Ctr, Jerusalem, IsraelHadassah Hebrew Univ, Med Ctr, Dept Oral Med Sedat & Maxillofacial Imaging, Jerusalem, Israel
Aframlan, D. J.
Keshet, N.
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Hadassah Hebrew Univ, Med Ctr, Dept Oral Med Sedat & Maxillofacial Imaging, Jerusalem, Israel
Hadassah Hebrew Univ, Med Ctr, Siogrens Syndrome Ctr, Jerusalem, IsraelHadassah Hebrew Univ, Med Ctr, Dept Oral Med Sedat & Maxillofacial Imaging, Jerusalem, Israel
Keshet, N.
Koplewitz, B.
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Hadassah Hebrew Univ, Med Ctr, Dept Med Imaging, Jerusalem, IsraelHadassah Hebrew Univ, Med Ctr, Dept Oral Med Sedat & Maxillofacial Imaging, Jerusalem, Israel
Koplewitz, B.
Nadler, C.
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Hadassah Hebrew Univ, Med Ctr, Dept Oral Med Sedat & Maxillofacial Imaging, Jerusalem, Israel
Hadassah Hebrew Univ, Med Ctr, Siogrens Syndrome Ctr, Jerusalem, IsraelHadassah Hebrew Univ, Med Ctr, Dept Oral Med Sedat & Maxillofacial Imaging, Jerusalem, Israel
Nadler, C.
ISRAEL MEDICAL ASSOCIATION JOURNAL,
2016,
18
(12):
: 770
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770