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Pulmonary Arterial Hypertension

被引：65
|
作者：
Dodson, Mark W. [1 ]
Brown, Lynette M. [1 ,2 ]
Elliott, Charles Gregory [1 ,2 ]
机构：
[1] Intermt Med Ctr, Dept Med, 5121 South Cottonwood St,Bldg 2,Suite 307, Murray, UT 84107 USA
[2] Univ Utah, Pulm Div, 24 North 1900 East,Wintrobe Bldg,Room 701, Salt Lake City, UT 84132 USA
来源：
HEART FAILURE CLINICS | 2018年 / 14卷 / 03期
关键词：
Pulmonary hypertension; Pulmonary arterial hypertension; BMPR2; REVEAL Registry; Phosphodiesterase-5; inhibitors; Endothelin receptor antagonists; Prostacyclin; ENDOTHELIN-RECEPTOR ANTAGONIST; CALCIUM-CHANNEL BLOCKERS; BLOOD-STREAM INFECTIONS; 2015 ESC/ERS GUIDELINES; CAPILLARY HEMANGIOMATOSIS; COMBINATION THERAPY; ORAL TREPROSTINIL; EIF2AK4; MUTATIONS; DOUBLE-BLIND; SURVIVAL;
D O I：
10.1016/j.hfc.2018.02.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This article provides an overview of pulmonary arterial hypertension (PAH), beginning with the initial pathologic recognition of pulmonary hypertension more than 100 years ago and progressing to the current diagnostic categorization of PAH. It reviews the epidemiology, pathophysiology, genetics, and modern treatment of PAH. The article discusses several important recent studies that have highlighted the importance of new management strategies, including serial risk assessment and combination pharmacotherapy.
引用
收藏
页码：255 / +
页数：16
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