Contouring of the Pharyngeal Superior Constrictor Muscle (PSCM). A cooperative study of the Italian Association of Radiation Oncology (AIRO) Head and Neck Group

被引:14
|
作者
Alterio, Daniela [1 ]
Ciardo, Delia [1 ]
Preda, Lorenzo [2 ]
Argenone, Angela [3 ]
Caspiani, Orietta [4 ]
Micera, Renato [5 ]
Redda, Maria G. Ruo [6 ]
Russi, Elvio G. [7 ]
Bianchi, Ernestina [8 ]
Orlandi, Ester [9 ]
Bacigalupo, Almalina [10 ]
Busetto, Mario [11 ]
Cante, Domenico [12 ]
Deantonio, Letizia [13 ]
De Sanctis, Vitaliana [14 ]
Franco, Pierfrancesco [15 ]
Lastrucci, Luciana [16 ]
Marucci, Laura [17 ]
Merlotti, Anna [18 ]
Molteni, Marinella [19 ]
Pajar, Fabiola [20 ]
Rampino, Monica [21 ]
Santoro, Luigi [22 ]
Ferrari, Annamaria [1 ]
Bazzani, Federica [1 ]
Caputo, Mariangela [1 ]
Laudati, Antonio [8 ]
Borzillo, Valentina [3 ]
Falivene, Sara [23 ]
Simoni, Nicola [5 ]
Vigo, Federica [5 ]
Iannacone, Eva [9 ]
Reali, Alessia [7 ]
Bonanni, Alessio [4 ]
Leone, Mariavittoria [4 ]
Giannello, Luca [7 ]
Taglianti, Riccardo Vigna [7 ]
Orecchia, Roberto [1 ,24 ]
机构
[1] European Inst Oncol, Adv Radiotherapy Ctr, Milan, Italy
[2] Ist Europeo Oncol, Div Radiol, Milan, Italy
[3] Fdn G Pascale IRCCS Napoli, Isr Nazl Studio & Cura Tumori, Naples, Italy
[4] Osped Fatebenefratelli Isola Tiberina, Rome, Italy
[5] Osped S Maria Nuova, Reggio Emilia, Italy
[6] Univ Turin, Azienda Osped Univ San Luigi Gonzaga Orbassano, I-10124 Turin, Italy
[7] Osped S Croce & Carle, Cuneo, Italy
[8] Osped S Anna Como, Como, Italy
[9] Fdn IRCSS Ist Nazl Tumori, Milan, Italy
[10] IRCSS AOU San Martino IST, Genoa, Italy
[11] Osped Angelo, Venice, Italy
[12] Osped Ivrea, Piemonte, Italy
[13] Univ Piemonte Orientate, SC Radioterapia AOU Maggiore Carita, Novara, Italy
[14] Univ Roma La Sapienza, Dipartimento Sci Med Chirurg & Med Translaz, Rome, Italy
[15] AUSL Valle Aosta, Dept Radiat Oncol, TomoTherapy Unit, Aosta, Italy
[16] Osped S Donato Arezzo, UOC Radioterapia, Arezzo, Italy
[17] Ist Nazl Tumori Regina Elena, Rome, Italy
[18] Azienda Osped Busto Arsizio, Varese, Italy
[19] Osped Circolo Varese, Varese, Italy
[20] Univ Florence, Aziendo Osped Univ Careggi, I-50121 Florence, Italy
[21] Univ Turin, Osped S Giovanni Battista, I-10124 Turin, Italy
[22] Ist Europeo Oncol, Div Epidemiol & Biostat, Milan, Italy
[23] Univ Naples 2, Naples, Italy
[24] Univ Milan, I-20122 Milan, Italy
关键词
Pharyngeal constrictor muscles; Dysphagia; Toxicity; Head and neck cancer; IMRT; INTENSITY-MODULATED RADIOTHERAPY; LOCALLY ADVANCED HEAD; SWALLOWING DYSFUNCTION; CANCER; DYSPHAGIA; CHEMORADIATION; ASPIRATION; TOXICITY; LARYNX;
D O I
10.1016/j.radonc.2014.05.016
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background and purpose: Irradiation of the Pharyngeal Superior Constrictor Muscle (PSCM) seems to play a crucial role in radiation-related swallowing dysfunctions. Purpose of our study was to quantify operator-related variability in the contouring of PSCM on Computed Tomography (CT) scans and adherence with contours derived from MR images. Materials and methods: Three sets of treatment planning CT and their corresponding MR images were selected. Contouring of the PSCM was performed using both a literature-based method, derived from literature review, and an optimized method, derived from Magnetic Resonance (MR) images thus obtaining "literature-based" and "optimized" contours. Each operator contoured the PSCM on CT scans according to both methods for three times in three different days. Inter- and intra-operator variability and adherence to a contour obtained from MR images (named "MR-derived" contour) were analyzed. Results: Thirty-four operators participated and 612 contours were obtained. Both intra- and inter-operator variability and adherence to the "MR-derived" contour were significantly different between the two methods (p <= 0.05). The "optimized" method showed a lower intra- and inter-operator variability and a higher adherence to the "MR-derived" contour. Conclusions: The "optimized" method ameliorates both operator-related variability and adherence with MR images. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:337 / 342
页数:6
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