Combining immunotherapy and radiotherapy for the STAR treatment

被引:28
|
作者
Torok, Jordan A. [1 ,2 ]
Salama, Joseph K. [1 ,2 ,3 ]
机构
[1] Duke Univ, Sch Med, Dept Radiat Oncol, Durham, NC 27708 USA
[2] Duke Canc Inst, Durham, NC 27710 USA
[3] Durham Vet Affairs Med Ctr, Radiat Oncol Serv, Durham, NC 27705 USA
关键词
MULTICENTER; THERAPY; CANCER;
D O I
10.1038/s41571-019-0277-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In the past few years, efforts have been made to combine two approaches - immune-checkpoint inhibition and locally ablative radiation therapy - to treat patients with metastatic non-small-cell lung cancer. Herein we discuss the implications of two studies that support the existence of a systemic therapy augmented by radiotherapy (STAR) effect in this setting.
引用
收藏
页码:666 / 667
页数:3
相关论文
共 50 条
  • [21] Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift
    Formenti, Silvia C.
    Demaria, Sandra
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2013, 105 (04): : 256 - 265
  • [22] Opportunities and challenges in combining immunotherapy and radiotherapy in esophageal cancer
    Zhang, Xinyu
    Cai, Xinsheng
    Yan, Chaoguang
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023, 149 (20) : 18065 - 18080
  • [23] Combining immunotherapy and radiotherapy in lung cancer: a promising future?
    Zhou, Jieling
    Huang, Qian
    Huang, Zijian
    Li, Jiqiang
    JOURNAL OF THORACIC DISEASE, 2020, 12 (08) : 4498 - 4503
  • [24] Opportunities and challenges in combining immunotherapy and radiotherapy in esophageal cancer
    Xinyu Zhang
    Xinsheng Cai
    Chaoguang Yan
    Journal of Cancer Research and Clinical Oncology, 2023, 149 : 18253 - 18270
  • [25] The role of combining immunotherapy with primary (Chemo)radiotherapy in curative treatment settings of the head and neck cancer
    Dua, Divyanshu
    Kelly, Charles
    Kovarik, Josef
    Iqbal, Muhammad Shahid
    ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022, 18 (02) : E3 - E10
  • [26] Combining immunotherapy with radiation for the treatment of glioblastoma
    Chow, Kevin K. H.
    Hara, Wendy
    Lim, Michael
    Li, Gordon
    JOURNAL OF NEURO-ONCOLOGY, 2015, 123 (03) : 459 - 464
  • [27] Combining immunotherapy with radiation for the treatment of glioblastoma
    Kevin K. H. Chow
    Wendy Hara
    Michael Lim
    Gordon Li
    Journal of Neuro-Oncology, 2015, 123 : 459 - 464
  • [28] Silvia Formenti on the promise of combining radiotherapy and immunotherapy to treat cancer
    Formenti, Silvia C.
    ONCOLOGY-NEW YORK, 2016, 30 (04): : 289 - +
  • [29] Opportunities and challenges in combining immunotherapy and radiotherapy in head and neck cancers
    Wong, Kenneth C. W.
    Johnson, David
    Hui, Edwin P.
    Lam, Rachel C. T.
    Ma, Brigette B. Y.
    Chan, Anthony T. C.
    CANCER TREATMENT REVIEWS, 2022, 105
  • [30] Smart Radiotherapy Biomaterials for Combining Radiotherapy and Immunotherapy With Image-Guided Radiotherapy and Drug Delivery Capability
    Moreau, M.
    Ziberi, B.
    Yasmin-Karim, S.
    Mueller, R.
    Kozono, D. E.
    Yelleswarapu, C. S.
    Ngwa, W.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2020, 108 (03): : E372 - E372