Applications of Chiral Squaramides: From Asymmetric Organocatalysis to Biologically Active Compounds

被引：75
|
作者：
Han, Xin [1 ]
Zhou, Hai-Bing [1 ]
Dong, Chune [1 ,2 ]
机构：
[1] Wuhan Univ, Sch Pharmaceut Sci, Minist Educ,State Key Lab Virol, Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China
来源：
CHEMICAL RECORD | 2016年 / 16卷 / 02期
关键词：
applications; asymmetric synthesis; drug discovery; squaramides; CATALYZED CONJUGATE ADDITION; VINYLOGOUS MICHAEL ADDITION; DYNAMIC KINETIC RESOLUTION; ENANTIOSELECTIVE SYNTHESIS; CASCADE REACTION; CINCHONINE-SQUARAMIDE; DERIVATIVES; EFFICIENT; ENONES; ACID;
D O I：
10.1002/tcr.201500266
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This review seeks to provide coverage on the recent advances in chiral squaramide-catalyzed asymmetric transformations and their applications in the synthesis of a variety of chiral biologically active compounds. It aims to give an overview highlighting the new reaction types and enantioenriched medicinal scaffolds developed in the last few years.
引用
收藏
页码：897 / 906
页数：10
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