Applications of Chiral Squaramides: From Asymmetric Organocatalysis to Biologically Active Compounds

被引：75
|
作者：
Han, Xin [1 ]
Zhou, Hai-Bing [1 ]
Dong, Chune [1 ,2 ]
机构：
[1] Wuhan Univ, Sch Pharmaceut Sci, Minist Educ,State Key Lab Virol, Lab Combinatorial Biosynth & Drug Discovery, Wuhan 430071, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China
来源：
CHEMICAL RECORD | 2016年 / 16卷 / 02期
关键词：
applications; asymmetric synthesis; drug discovery; squaramides; CATALYZED CONJUGATE ADDITION; VINYLOGOUS MICHAEL ADDITION; DYNAMIC KINETIC RESOLUTION; ENANTIOSELECTIVE SYNTHESIS; CASCADE REACTION; CINCHONINE-SQUARAMIDE; DERIVATIVES; EFFICIENT; ENONES; ACID;
D O I：
10.1002/tcr.201500266
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This review seeks to provide coverage on the recent advances in chiral squaramide-catalyzed asymmetric transformations and their applications in the synthesis of a variety of chiral biologically active compounds. It aims to give an overview highlighting the new reaction types and enantioenriched medicinal scaffolds developed in the last few years.
引用
收藏
页码：897 / 906
页数：10
相关论文
共 50 条
  • [1] Primary and secondary amine-(thio)ureas and squaramides and their applications in asymmetric organocatalysis
    Tsakos, Michail
    Kokotos, Christoforos G.
    TETRAHEDRON, 2013, 69 (48) : 10199 - 10222
  • [2] Use of chiral auxiliaries in the asymmetric synthesis of biologically active compounds: A review
    Diaz-Munoz, Gaspar
    Miranda, Izabel Luzia
    Sartori, Suelen Karine
    de Rezende, Daniele Cristina
    Nogueira Diaz, Marisa Alves
    CHIRALITY, 2019, 31 (10) : 776 - 812
  • [3] Construction of Axially Chiral Compounds via Asymmetric Organocatalysis
    Wang, Yong-Bin
    Tan, Bin
    ACCOUNTS OF CHEMICAL RESEARCH, 2018, 51 (02) : 534 - 547
  • [4] Asymmetric organocatalysis by chiral Bronsted bases: implications and applications
    Palomo, Claudio
    Oiarbide, Mikel
    Lopez, Rosa
    CHEMICAL SOCIETY REVIEWS, 2009, 38 (02) : 632 - 653
  • [5] Asymmetric lodolactonization Utilizing Chiral Squaramides
    Tungen, Jorn E.
    Nolsoe, Jens M. J.
    Hansen, Trond V.
    ORGANIC LETTERS, 2012, 14 (23) : 5884 - 5887
  • [6] APPLICATIONS OF SULFOXIDES TO ASYMMETRIC-SYNTHESIS OF BIOLOGICALLY-ACTIVE COMPOUNDS
    CARRENO, MC
    CHEMICAL REVIEWS, 1995, 95 (06) : 1717 - 1760
  • [7] Asymmetric synthesis of biologically active compounds
    Kagan, H
    ACTUALITE CHIMIQUE, 2003, (11-12): : 10 - 14
  • [8] ASYMMETRIC-SYNTHESIS OF BIOLOGICALLY-ACTIVE COMPOUNDS BEARING A CHIRAL SULFINYL GROUP
    KHIAR, N
    FERNANDEZ, I
    ALCUDIA, F
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1993, 74 (1-4): : 405 - 406
  • [9] Recent advances in asymmetric catalysis. Synthetic applications to biologically active compounds
    Genet, JP
    Marinetti, A
    Ratovelomanana-Vidal, V
    PURE AND APPLIED CHEMISTRY, 2001, 73 (02) : 299 - 303
  • [10] Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis
    Aleman, Jose
    Parra, Alejandro
    Jiang, Hao
    Jorgensen, Karl Anker
    CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (25) : 6890 - 6899
12345