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- [24] Cytochrome P4502C19 loss-of-function polymorphism, but not CYP3A4 IVS10+12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients PHARMACOGENETICS AND GENOMICS, 2007, 17 (12): : 1057 - 1064