Recent progress in antiviral chemotherapy for respiratory syncytial virus infections

被引：34
|
作者：
Shigeta, S [1 ]
机构：
[1] Fukushima Med Univ, Sch Med, Dept Microbiol, Fukushima 9601295, Japan
来源：
EXPERT OPINION ON INVESTIGATIONAL DRUGS | 2000年 / 9卷 / 02期
关键词：
acute respiratory infections; antiviral chemotherapy; monoclonal antibody; respiratory syncytial virus; ribavirin;
D O I：
10.1517/13543784.9.2.221
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The recent progress in antiviral chemotherapy against respiratory syncytial virus (RSV) infections was reviewed. RSV infections among high risk individuals, such as premature babies, infants with congenital disease of cardiopulmonary system or immune system and the aged, hospitalised patients with immunosuppressed status are threatened, with high mortality rates and thus need anti-viral chemotherapy. Clinical efficacy of ribavirin and humanised monoclonal antibody (mAb) against RSV infections as well as experimental reports of novel anti-RSV compounds under investigation such as membrane fusion inhibitors were introduced.
引用
收藏
页码：221 / 235
页数：15
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