Sustainable pectin fascinating hydroxyapatite nanocomposite scaffolds to enhance tissue regeneration

The preparation of biocompatible nanomaterials is one of the emerging areas and it is continuously developing with the use of various contrived methods to accomplish the formation of nanoscale materials. Nevertheless, unfortunately, many of these strategies utilize harmful organic solvents, which make the pertinence of nanoparticles in medicinal applicationsimpractical. In this study, the morphology-focused hydroxyapatite (HAP) was prepared using pectin extracted from the citrus fruit peel (Citrus limonum) and it is used for the synthesis of nano HAP by varying the concentration of pectin as a template. The chemical structure, crystallinity, and morphology were determined by FTIR, XRD, and SEM, respectively. To increase the biocompatibility of HAP, pectin aided HAP (tHAP) and HAP/pectin composites were synthesized with different concentrations of pectin. The compatibility of HAP/pectin was carried out in a human osteoblast cell line. The physic-chemical and biocompatibility showed, HAP/pectin, and HAP/pectin composites are promising materials for bone tissue engineering applications.