Chemical Composition and In Vitro Antimicrobial Activity of the Essential Oil Obtained from Eugenia pyriformis Cambess. (Myrtaceae)

被引:5
|
作者
de Souza, Angela Maria [1 ]
de Oliveira, Vinicius Bednarczuk [1 ]
de Oliveira, Camila Freitas [1 ]
Martins Betim, Fernando Cesar [1 ]
Golin Pacheco, Samanta Daliana [1 ]
Cogo, Laura Lucia [2 ]
Miguel, Obdulio Gomes [1 ]
Miguel, Marilis Dallarmi [1 ]
机构
[1] Univ Fed Parana, Dept Pharm, Postgrad Program Pharmaceut Sci, Curitiba, Parana, Brazil
[2] Univ Fed Parana, Hosp Clin, Unit Lab Clin Analyzes, Sect Microbiol, Curitiba, Parana, Brazil
关键词
Eugenia pyriformis; chemical composition; essential oil; antimicrobial activity; MEDICINAL-PLANTS; UNIFLORA L; LEAVES; LEAF; CONSTITUENTS; ANTIOXIDANT; TOXICITY;
D O I
10.1590/1678-4324-2021200663
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Our study aimed to evaluate the chemical composition of the essential oil from the leaves of Eugenia pyriformis Cambess., belonging to the Myrtaceae family and native to the Brazilian Atlantic forest. The volatile compounds in the essential oil were extracted by hydrodistillation and analyzed using GC-MS; 36 compounds accounted for 78.80% of the total oil content. The major compounds were beta- caryophyllene, bicyclogermacrene, globulol, and delta-cadinene. We evaluated their antimicrobial potential of the essential oil and toxicity to Artemia salina. The antimicrobial activity of the essential oil was evaluated against 12 microorganisms using the broth microdilution method. Our results showed moderate inhibition of Staphylococcus aureus and methicillin-resistant S. aureus (MIC, 250 and 125 mu g.mL(-1), respectively) and toxicity to A. salina (LC50, 125.64 mu g.mL(-1)). Our results establish the biological activity of the essential oil obtained from E. pyriformis.
引用
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页码:1 / 10
页数:10
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