Rigid Region Pairwise Sequence Alignment

被引:0
|
作者
Zivanic, Marko [1 ]
Daescu, Ovidiu [1 ]
Kurdia, Anastasia [2 ]
机构
[1] Univ Texas Dallas, 800 W Campbell Rd, Richardson, TX 75080 USA
[2] Smith Coll, 7 Coll Lane, Northampton, MA 01063 USA
关键词
Protein sequence alignment; protein rigidity and flexibility; protein structure prediction;
D O I
暂无
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
We initiate a formal study of correlation between protein structural similarity and similarity of protein rigidity properties. In this paper we combine algorithmic techniques from protein sequence alignment and protein rigidity analysis and derive a new algorithm for protein sequence alignment, ultimately aiming at improving accuracy of protein homology detection and structure prediction, and also reducing the running time of currently known methods.
引用
收藏
页码:319 / 326
页数:8
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