A 28-year-old woman with fever, rash, and pancytopenia

被引：3

作者：

Ochoa, Sebastian ^{[1
]}

Cheng, Kyle ^{[2
]}

Fleury, Christine M. ^{[3
]}

Luccioli, Stefano ^{[4
]}

Bellanti, Joseph A. ^{[5
,6
]}

机构：

[1] Medstar Georgetown Univ Hosp, Dept Internal Med, Washington, DC USA

[2] Medstar Georgetown Univ Hosp, Dept Dermatol, Washington, DC USA

[3] Medstar Georgetown Univ Hosp, Dept Pulm & Crit Care Med, Washington, DC USA

[4] US FDA, Off Food Addit Safety, Ctr Food Safety & Appl Nutr, College Pk, MD USA

[5] Georgetown Univ, Med Ctr, Int Ctr Interdisciplinary Studies Immunol, Washington, DC 20007 USA

[6] Georgetown Univ, Sch Med, Washington, DC USA

来源：

ALLERGY AND ASTHMA PROCEEDINGS | 2017年 / 38卷 / 04期

关键词：

HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; SYSTEMIC SYMPTOMS; DRUG REACTION; EOSINOPHILIA;

D O I：

10.2500/aap.2017.38.4042

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

A 28-year-old Hispanic woman was admitted to the hospital with fever, sore throat, arthralgia, and a generalized rash of 2 weeks' duration. Her medical history was significant for various food and medication allergies. Multiple antibiotics were given for suspected infection, and she subsequently developed a new skin rash, acute liver injury, eosinophilia, and pancytopenia. Additional studies showed hypertriglyceridemia; elevated interleukin-2 receptor levels; absent natural killer cell activity; and hemophagocytosis in skin, liver, and bone marrow biopsy specimens. Treatment with intravenous immunoglobulin and steroids resulted in complete remission.

引用

页码：322 / 327

页数：6

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