Two new diterpenoid lactones isolated from Andrographis paniculata

被引：11
|
作者：
Wang Gui-Yang [1 ,2 ]
Wen Ting [1 ,2 ]
Liu Fei-Fei [1 ,2 ]
Tian Hai-Yan [1 ]
Fan Chun-Lin [1 ,2 ]
Huang Xiao-Jun [1 ,2 ]
Ye Wen-Cai [1 ,2 ]
Wang Ying [1 ,2 ]
机构：
[1] Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
[2] Jinan Univ, Coll Pharm, JNU HKUST Joint Lab Neurosci & Innovat Drug Res, Guangzhou 510632, Guangdong, Peoples R China
来源：
CHINESE JOURNAL OF NATURAL MEDICINES | 2017年 / 15卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Acanthaceae; Andrographis paniculata; Diterpenoid lactones; ENT-LABDANE DITERPENOIDS;
D O I：
10.1016/S1875-5364(17)30068-7
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
In the present study, two new diterpenoid lactones, 3-deoxy-andrographoside (1) and 14-deoxy-15-methoxy-andrographolide (2), were isolated from the aerial parts of Andrographis paniculata. Their structures were elucidated by combination of NMR, MS, and chemical methods. The configurations of 1 and 2 were established based on the analysis of ROESY data and single crystal X-ray diffraction experiment.
引用
收藏
页码：458 / 462
页数：5
相关论文
共 50 条
  • [41] Antinociceptive and Antiedematogenic Activities of Andrographolide Isolated From Andrographis paniculata in Animal Models
    Sulaiman, M. R.
    Zakaria, Z. A.
    Rahman, A. Abdul
    Mohamad, A. S.
    Desa, M. N.
    Stanslas, J.
    Moin, S.
    Israf, D. A.
    BIOLOGICAL RESEARCH FOR NURSING, 2010, 11 (03) : 293 - 301
  • [42] Variation in growth and diterpene lactones among field-cultivated Andrographis paniculata
    Sompop Prathanturarug
    Noppamas Soonthornchareonnon
    Wongsatit Chuakul
    Promjit Saralamp
    Journal of Natural Medicines, 2007, 61 : 159 - 163
  • [43] Cardiovascular Activity of Labdane Diterpenes from Andrographis paniculata in Isolated Rat Hearts
    Awang, Khalijah
    Abdullah, Nor Hayati
    Hadi, A. Hamid A.
    Fong, Yew Su
    JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2012,
  • [44] Diterpenoids and Flavonoids from Andrographis paniculata
    Tran Thi Hong Hanh
    Nguyen Thi Thuy My
    Pham Thi Cham
    Tran Hong Quang
    Nguyen Xuan Cuong
    Tran Thu Huong
    Nguyen Hoai Nam
    Chau Van Minh
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 68 (01) : 96 - 99
  • [45] Secondary metabolites from Andrographis paniculata
    Li, Wenkui
    Xu, Xudong
    Zhang, Hongjie
    Ma, Cuiying
    Fong, Harry
    van Breemen, Richard
    Fitzloff, John
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55 (03) : 455 - 458
  • [46] In Vitro Antiprotozoal Activity of Some Xanthones Isolated from the Roots of Andrographis paniculata
    Dua, Virendra K.
    Verma, Gaurav
    Dash, A. P.
    PHYTOTHERAPY RESEARCH, 2009, 23 (01) : 126 - 128
  • [47] Comparison of diterpenoid contents and dissolution profiles of selected Andrographis paniculata crude and extract capsules
    Rangkadilok, Nuchanart
    Pholphana, Nanthanit
    Akanimanee, Jaratluck
    Panomvana, Duangchit
    Puranajoti, Porranee
    Songvut, Phanit
    Satayavivad, Jutamaad
    PHYTOCHEMICAL ANALYSIS, 2024, 35 (06) : 1309 - 1322
  • [48] Antiallergic activity of Andrographolides isolated from Andrographis paniculata (Burm F) Wall
    Gupta, PP
    Tandon, JS
    Patnaik, GK
    PHARMACEUTICAL BIOLOGY, 1998, 36 (01) : 72 - 74
  • [49] The genome of the medicinal plant Andrographis paniculata provides insight into the biosynthesis of the bioactive diterpenoid neoandrographolide
    Sun, Wei
    Leng, Liang
    Yin, Qinggang
    Xu, MeiMei
    Huang, Mingkun
    Xu, Zhichao
    Zhang, Yujun
    Yao, Hui
    Wang, Caixia
    Xiong, Chao
    Chen, Sha
    Jiang, Chunhong
    Xie, Ning
    Zheng, Xilong
    Wang, Ying
    Song, Chi
    Peters, Reuben J.
    Chen, Shilin
    PLANT JOURNAL, 2019, 97 (05): : 841 - 857
  • [50] A new ent-labdane eiterpenoid lactone from Andrographis paniculata
    Xiao Chi Ma~(a
    Chinese Chemical Letters, 2009, 20 (03) : 317 - 319
12345