Nf1 plays an essential role in osteoclasts development via hyperactivation of Ras-PI3K signaling.

被引:0
|
作者
Chen, S
Ingram, DA
Wenning, MJ
Hock, J
Yang, FC
Clapp, DW
机构
[1] Herman B Wells Ctr Pediat Res, Dept Pediat, Indianapolis, IN USA
[2] Indiana Univ, Sch Med, Dept Immunol Microbiol, Indianapolis, IN 46204 USA
关键词
D O I
10.1182/blood.V104.11.1462.1462
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1462
引用
收藏
页码:409A / 409A
页数:1
相关论文
共 50 条
  • [21] NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development
    Sanchez-Ortiz, Efrain
    Cho, Woosung
    Nazarenko, Inga
    Mo, Wei
    Chen, Jian
    Parada, Luis F.
    GENES & DEVELOPMENT, 2014, 28 (21) : 2407 - 2420
  • [22] Mutations of Cyclin D1 / beta-catenin are coexistent with mutations in Ras-PI3K pathway genes in endometrial cancer
    Ikeda, Yuji
    Oda, Katsutoshi
    Nakagawa, Shunsuke
    Shoji, Keiko
    Kashiyama, Tomoko
    Ishikawa, Shumpei
    Yamamoto, Shogo
    Tanikawa, Michihiro
    Hiraike, Osamu
    Aburatani, Hiroyuki
    Yano, Tetsu
    Taketani, Yuji
    CANCER RESEARCH, 2011, 71
  • [23] Androgen Plays a Carcinogenic Role in EOC via the PI3K/AKT Signaling Pathway in an AR-Dependent Manner
    Li, Yanfang
    Li, Sha
    Zhang, Yizhou
    Shi, Shuhong
    Qin, Shan
    Wang, Chang
    Du, Juan
    Ma, Jingle
    Chen, Huan
    Cui, Huixian
    JOURNAL OF CANCER, 2021, 12 (06): : 1815 - 1825
  • [24] Avβ3 Single-Stranded DNA Aptamer Attenuates Vascular Smooth Muscle Cell Proliferation and Migration via Ras-PI3K/MAPK Pathway
    Wu, Hong-Bing
    Wang, Zhi-Wei
    Shi, Feng
    Ren, Zong-Li
    Li, Luo-Cheng
    Hu, Xiao-Ping
    Hu, Rui
    Li, Bo-Wen
    CARDIOVASCULAR THERAPEUTICS, 2020, 2020
  • [25] Interleukin-1β Plays a Pivotal Role via the PI3K/Akt/mTOR Signaling Pathway in the Chronicity of Mesial Temporal Lobe Epilepsy
    Xiao, Zhaohua
    Peng, Jing
    Gan, Na
    Arafat, Ahmed
    Yin, Fei
    NEUROIMMUNOMODULATION, 2016, 23 (5-6) : 332 - 344
  • [26] IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/ IKK/NF- κ B signaling pathways to promote wound healing
    Zhang, Xin
    Hu, Fei
    Li, Jie
    Chen, Lin
    Mao, Yu-fei
    Li, Qiu-bo
    Nie, Chen-yao
    Lin, Cai
    Xiao, Jian
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2024, 200
  • [27] Role of nuclear PLC and PI3K signaling in the development of cancer
    Faenza, Irene
    Ramazzotti, Giulia
    Bavelloni, Alberto
    Bregoli, Lisa
    Fiume, Roberta
    Gaboardi, Gian Carlo
    Manzoli, Lucia
    Matteucet, Alessandro
    Martelli, Alberto M.
    Cocco, Lucio
    FUTURE LIPIDOLOGY, 2007, 2 (03): : 303 - 311
  • [28] The Role of PI3K/AKT Signaling in the Development of Ciona intestinalis
    Evans-Anderson, Heather J.
    Tucker, James
    Intwala, Arti
    FASEB JOURNAL, 2013, 27
  • [29] Essential role of RAS and PI3K pathways in Flt3 dependent proliferation and survival.
    Mizuki, M
    Fenski, R
    Serve, S
    Matsumura, I
    Grüning, W
    Kratz-Albers, K
    Büchner, T
    Berdel, WE
    Kanakura, Y
    Serve, H
    BLOOD, 1999, 94 (10) : 262A - 263A
  • [30] FGFR3 mutations associated with acanthosis nigricans increase keratinocyte survival via PI3-K/Akt signaling.
    Bellus, GA
    Janik, J
    Kelly, DP
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (04) : 648 - 648