High-dose quetiapine and therapeutic monitoring

被引：4
|
作者：
Javelot, Herve [1 ]
Rangoni, Francis [2 ]
Weiner, Luisa [3 ]
Michel, Bruno [4 ]
机构：
[1] Etab Publ Sante Alsace Nord, Serv Pharm Clin, Brumath, France
[2] Etab Publ Sante Alsace Nord, Pole G07, Brumath, France
[3] CHU Strasbourg, Civil Hosp, Psychiat 2, Strasbourg, France
[4] Hop Univ Strasbourg, Serv Pharm, Strasbourg, France
来源：
EUROPEAN JOURNAL OF HOSPITAL PHARMACY | 2019年 / 26卷 / 05期
关键词：
psychiatry; therapeutic drug monitoring; antipsychotics; quetiapine; resistant schizophrenia; PSYCHIATRY WFSBP GUIDELINES; BIOLOGICAL TREATMENT; WORLD FEDERATION; CYTOCHROME-P450; ENZYMES; ACTIVE METABOLITE; UPDATE; 2012; PHARMACOKINETICS; SCHIZOPHRENIA; VARIABILITY; MANAGEMENT;
D O I：
10.1136/ejhpharm-2018-001605
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Quetiapine is an atypical antipsychotic with a good safety profile permitting its administration beyond the maximum dose of 800 mg/day. We report the case of a patient with a resistant schizophrenia treated with high doses of quetiapine (up to 2000 mg/day) combined with drug monitoring and with favourable therapeutic response and tolerance.
引用
收藏
页码：285 / 287
页数：3
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