AAV9 Transduction Is Similar in Adult and Aged Mouse Brains Following Intraparenchymal Injection

被引:0
|
作者
Gombash, Sara E. [1 ]
Fitzgerald, Julie A. [1 ]
Cowley, Christopher J. [1 ]
Neides, Mitchell G. [1 ]
Armstrong, Emily [1 ]
Norden, Diana M. [2 ]
Godbout, Jonathan P. [1 ]
Foust, Kevin D. [1 ]
机构
[1] Ohio State Univ, Neurosci, Columbus, OH 43210 USA
[2] Ohio State Univ, Phys Therapy, Columbus, OH 43210 USA
关键词
D O I
10.1016/S1525-0016(16)33427-X
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
619
引用
收藏
页码:S245 / S245
页数:1
相关论文
共 50 条
  • [11] Transduction and Expression in Brain after Systemic Delivery of Single Stranded AAV9 in Adult Mice
    Keeler, Allison M.
    Sena-Esteves, Miguel
    Conlon, Thomas
    Erger, Kirsten
    Fu Dongtao
    Flotte, Terence R.
    MOLECULAR THERAPY, 2012, 20 : S228 - S228
  • [12] CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain
    Mathiesen, Sophie N.
    Lock, Jasmine L.
    Schoderboeck, Lucia
    Abraham, Wickliffe C.
    Hughes, Stephanie M.
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2020, 19 : 447 - 458
  • [13] The human brain endothelial barrier: transcytosis of AAV9, transduction by AAV2
    Weber-Adrian, Danielle
    Heinen, Stefan
    Silburt, Joseph
    Noroozian, Zeinab
    Aubert, Isabelle
    JOURNAL OF NEUROCHEMISTRY, 2017, 140 (02) : 192 - 194
  • [14] Comparing AAV2 and AAV9 tropism and transgene expression in mouse tissues after intravitreal and subretinal injection
    Koponen, S.
    Kokki, E.
    Tamminen, T.
    Yla-Herttuala, S.
    HUMAN GENE THERAPY, 2024, 35 (3-4) : A104 - A104
  • [15] Enhanced Cochlear Transduction by AAV9 with High-Concentration Sucrose
    Noda, Masao
    Koshu, Ryota
    Dias, Mari Shimada
    Saito, Chizu
    Takino, Naomi
    Ito, Mika
    Yoshimura, Hidekane
    Ito, Makoto
    Muramatsu, Shin-ichi
    HUMAN GENE THERAPY, 2023, 34 (19-20) : 1064 - 1071
  • [16] Pretreatment with IVIG Reduces Peripheral Transduction of AAV9 Delivered to the CNS
    West, Cara
    Mastis, Bryan
    Vandenberghe, Luk H.
    Richman, Laura K.
    Calcedo, Roberto
    MOLECULAR THERAPY, 2022, 30 (04) : 21 - 21
  • [17] The synapsin promoter drives expression in liver and other viscera following neonatal AAV9 injection
    Ng, Joanne
    Rahim, Ahad
    Kurian, Manju
    Waddington, Simon
    HUMAN GENE THERAPY, 2015, 26 (09) : A25 - A25
  • [18] Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9
    Chatterjee, Diptaman
    Marmion, David J.
    McBride, Jodi L.
    Manfredsson, Fredric P.
    Butler, David
    Messer, Anne
    Kordower, Jeffrey H.
    GENE THERAPY, 2022, 29 (06) : 390 - 397
  • [19] Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9
    Diptaman Chatterjee
    David J. Marmion
    Jodi L. McBride
    Fredric P. Manfredsson
    David Butler
    Anne Messer
    Jeffrey H. Kordower
    Gene Therapy, 2022, 29 : 390 - 397
  • [20] AAV9 Capsid Variants with Improved CNS Transduction Identified by Directed Evolution
    Rohovie, Marcus
    Kruse, Nikki
    Schmitt, Christopher
    Wong, Victoria
    Sero, Antoinette
    Rivera-Velazquez, Mirella
    Lee, Grace
    Desautel, Sarah
    Del Greco, Elizabeth
    Sedighi, Faezeh
    Nivina, Aleksandra
    Jenne, Stephan
    Gebretsadik, Kahsay
    Kumar, Ambuj
    Chng, Chinping
    Akeefe, Hassibullah
    Silverman, Adam
    MOLECULAR THERAPY, 2023, 31 (04) : 661 - 661