Transgenic mice over-expressing Dkk-1 in osteoblasts develop osteoporosis.

被引:0
|
作者
Li, J [1 ]
Sarosi, I [1 ]
Morony, SE [1 ]
Hill, D [1 ]
Wang, Y [1 ]
Qiu, W [1 ]
Adamu, S [1 ]
Grisanti, M [1 ]
Hoffmann, K [1 ]
Gyuris, T [1 ]
Nguyen, H [1 ]
Cattley, R [1 ]
Kostenuik, RJ [1 ]
Simonet, SS [1 ]
Lacey, DL [1 ]
机构
[1] Amgen Inc, Thousand Oaks, CA 91320 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:S6 / S6
页数:1
相关论文
共 50 条
  • [21] Echocardiographic and histopathological characterization of young and old transgenic mice over-expressing the human β1-adrenergic receptor
    Port, JD
    Weinberger, HD
    Bisognano, JD
    Knudson, OA
    Bohlmeyer, TJ
    Pende, A
    Bristow, MR
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1998, 31 (02) : 177A - 177A
  • [22] Production of transgenic pigs over-expressing the antiviral gene Mx1
    Yan Q.
    Yang H.
    Yang D.
    Zhao B.
    Ouyang Z.
    Liu Z.
    Fan N.
    Ouyang H.
    Gu W.
    Lai L.
    Cell Regeneration, 3 (1) : 3:11
  • [23] Over-expression of Dkk-1 in osteoblasts reduces bone mass but does not alter the anabolic response to intermittent PTH treatment in mice.
    Yao, GQ
    Wu, JJ
    Troiano, N
    Bartkiewicz, M
    Sun, BH
    Insogna, K
    JOURNAL OF BONE AND MINERAL RESEARCH, 2005, 20 (09) : S48 - S49
  • [24] Transgenic mice over-expressing cardiac Gsα develop QT prolongation and decreased transient outward K+ currents with slowed inactivation.
    Szigeti, GP
    Asai, K
    Kim, SJ
    Vatner, S
    Rasmusson, RL
    Yatani, A
    BIOPHYSICAL JOURNAL, 2000, 78 (01) : 341A - 341A
  • [25] Transgenic mice over-expressing human β-amyloid have functional nicotinic alpha 7 receptors
    Spencer, JP
    Weil, A
    Hill, K
    Hussain, I
    Richardson, JC
    Cusdin, FS
    Chen, YH
    Randall, AD
    NEUROSCIENCE, 2006, 137 (03) : 795 - 805
  • [26] Association of Serum Dkk-1 Levels with β-catenin in Patients with Postmenopausal Osteoporosis
    田峻
    徐晓娟
    沈霖
    杨艳萍
    朱锐
    帅波
    朱习文
    李成刚
    马陈
    吕林
    Current Medical Science, 2015, 35 (02) : 212 - 218
  • [27] Association of Serum Dkk-1 Levels with β-catenin in Patients with Postmenopausal Osteoporosis
    Tian, Jun
    Xu, Xiao-juan
    Shen, Lin
    Yang, Yan-ping
    Zhu, Rui
    Shuai, Bo
    Zhu, Xi-wen
    Li, Cheng-gang
    Ma, Chen
    Lv, Lin
    JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES, 2015, 35 (02) : 212 - 218
  • [28] Role of altered osteoblastic expression of Dkk-1 in the pathogenesis of osteoarthritis and osteoporosis
    Corrado, A.
    Neve, A.
    Macchiarola, A.
    Gaudio, A. M.
    Marucci, A.
    Cantatore, F. P.
    BONE, 2011, 48 : S105 - S105
  • [29] Association of serum Dkk-1 levels with β-catenin in patients with postmenopausal osteoporosis
    Jun Tian
    Xiao-juan Xu
    Lin Shen
    Yan-ping Yang
    Rui Zhu
    Bo Shuai
    Xi-Wen Zhu
    Cheng-gang Li
    Chen Ma
    Lin Lv
    Journal of Huazhong University of Science and Technology [Medical Sciences], 2015, 35 : 212 - 218
  • [30] AMD-like phenotypes in transgenic mice over-expressing BMP4 in RPE
    Zhu, Danhong
    Xu, Jing
    Deng, Xuemei
    Hsiung, Jamie
    Ryan, Stephen
    Hinton, David
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (15)