Multi-modal single-cell profiling of sarcomas from archival tissue reveals mechanisms of resistance to immune checkpoint inhibitors

被引:0
|
作者
Bose, Sminu [1 ]
Caldwell, Blake [1 ]
Amin, Amit Dipak [1 ]
Melms, Johannes [1 ]
Tagore, Somnath [1 ]
Ingham, Matthew [1 ]
Izar, Benjamin [1 ]
Schwartz, Gary K. [1 ]
机构
[1] Columbia Univ, Med Ctr, New York, NY USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PR006
引用
收藏
页数:2
相关论文
共 50 条
  • [21] SINGLE-CELL PROFILING REVEALS AGE-ASSOCIATED IMMUNE CELLS IN ATHEROSCLEROSIS
    Smit, V.
    De Mol, J.
    Schaftenaar, F.
    Depuydt, M. A. C.
    Postel, R.
    Smeets, D.
    Verheijen, F.
    Bogers, L.
    Van Duijn, J.
    Verwilligen, R.
    Grievink, H.
    Kleijn, M. Bernabe
    Goncalves, L.
    Peeters, J.
    Smeets, H.
    Wezel, A.
    Polansky-Biskup, J.
    De Winther, M.
    Binder, C.
    Tsiantoulas, D.
    Bot, I.
    Kuiper, J.
    Foks, A.
    ATHEROSCLEROSIS, 2023, 379
  • [22] Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis
    Unterman, Avraham
    Zhao, Amy Y.
    Neumark, Nir
    Schupp, Jonas C.
    Ahangari, Farida
    Cosme, Carlos
    Sharma, Prapti
    Flint, Jasper
    Stein, Yan
    Ryu, Changwan
    Ishikawa, Genta
    Sumida, Tomokazu S.
    Gomez, Jose L.
    Herazo-Maya, Jose D.
    Cruz, Charles S. Dela
    Herzog, Erica L.
    Kaminski, Naftali
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 210 (04) : 484 - 496
  • [23] Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib
    Peretz, Cheryl A. C.
    McGary, Lisa H. F.
    Kumar, Tanya
    Jackson, Hunter
    Jacob, Jose
    Durruthy-Durruthy, Robert
    Levis, Mark J.
    Perl, Alexander
    Huang, Benjamin J.
    Smith, Catherine C.
    BLOOD ADVANCES, 2021, 5 (05) : 1437 - 1441
  • [24] Single-cell RNA-sequencing and -imaging of melanoma ecosystems reveals sources of resistance to immune checkpoint blockade.
    Izar, Benjamin
    Jerby-Arnon, Livnat
    Rotem, Asaf
    Shah, Parin
    Liu, David
    Zhang, Gao
    Schilling, Bastian
    Rozenblatt-Rosen, Orit
    Boland, Genevieve Marie
    Hodi, F. Stephen
    Flaherty, Keith
    Van Allen, Eliezer Mendel
    Johnson, Bruce E.
    Schadendorf, Dirk
    Yoon, Charles
    Garraway, Levi A.
    Regev, Aviv
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [25] Multi-modal single-cell analysis of immunotherapy-experienced cutaneous and mucosal melanoma
    Biermann, Jana
    Wang, Yiping
    Fan, Linyue
    Ho, Patricia
    Amin, Amit D.
    Melms, Johannes C.
    Tagore, Somnath
    Hoffer-Hawlik, Kevin
    Shah, Parin
    Shaikh, Neha
    Ramaradj, Priyanka
    Zhang, Mingxuan
    Ribas, Antoni
    Robert, Caroline
    Azizi, Elham
    Izar, Benjamin
    CANCER RESEARCH, 2023, 83 (07)
  • [26] MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data
    Ricard Argelaguet
    Damien Arnol
    Danila Bredikhin
    Yonatan Deloro
    Britta Velten
    John C. Marioni
    Oliver Stegle
    Genome Biology, 21
  • [27] MOFA plus : a statistical framework for comprehensive integration of multi-modal single-cell data
    Argelaguet, Ricard
    Arnol, Damien
    Bredikhin, Danila
    Deloro, Yonatan
    Velten, Britta
    Marioni, John C.
    Stegle, Oliver
    GENOME BIOLOGY, 2020, 21 (01)
  • [28] GEEES: inferring cell-specific gene-enhancer interactions from multi-modal single-cell data
    Chen, Shuyang
    Keles, Sunduz
    BIOINFORMATICS, 2024, 40 (11)
  • [29] Single-cell profiling reveals dynamic epithelial and immune cell interactions in the progression of lung adenocarcinoma
    Chen, Hong
    Zhu, Bo
    Fujimoto, Junya
    Tian, Yanhua
    Li, Jian-Rong
    Li, Chenyang
    Chen, Pingjun
    Reuben, Alexandre
    Nilsson, Monique
    Le, Xiuning
    Poteete, Alissa
    Hubert, Shawna M.
    Gibbons, Don L.
    Wistuba, Ignacio I.
    Wu, Jia
    Cheng, Chao
    Heymach, John V.
    Zhang, Jianjun
    CANCER RESEARCH, 2024, 84 (06)
  • [30] Mechanisms of primary and acquired resistance to immune checkpoint inhibitors in advanced non-small cell lung cancer: A multiplex immunohistochemistry-based single-cell analysis
    Isomoto, Kohsuke
    Haratani, Koji
    Tsujikawa, Takahiro
    Makutani, Yusuke
    Kawakami, Hisato
    Takeda, Masayuki
    Yonesaka, Kimio
    Tanaka, Kaoru
    Iwasa, Tsutomu
    Hayashi, Hidetoshi
    Ito, Akihiko
    Nishio, Kazuto
    Nakagawa, Kazuhiko
    LUNG CANCER, 2022, 174 : 71 - 82