Insights into Chimeric Antigen Receptor Therapy for Chronic Lymphoblastic Leukemia

被引：0
|
作者：
Hamieh, Mohamad [1 ]
Sadelain, Michel [1 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Ctr Cell Engn, New York, NY 10065 USA
来源：
TRENDS IN MOLECULAR MEDICINE | 2018年 / 24卷 / 09期
关键词：
D O I：
10.1016/j.molmed.2018.06.007
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In a recent study, Fraietta and colleagues identified chimeric antigen receptor (CAR) T cell biomarkers that may predict the success or failure of CAR therapy in patients with refractorychroniclymphoblastic leukemia (CLL). These findings open new prospects for improving T cell product manufacturing and the management of patients with CLL undergoing T cell-based therapies.
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页码：729 / 731
页数：3
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