Insights into Chimeric Antigen Receptor Therapy for Chronic Lymphoblastic Leukemia

被引：0

作者：

Hamieh, Mohamad ^{[1
]}

Sadelain, Michel ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Ctr Cell Engn, New York, NY 10065 USA

来源：

TRENDS IN MOLECULAR MEDICINE | 2018年 / 24卷 / 09期

关键词：

D O I：

10.1016/j.molmed.2018.06.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In a recent study, Fraietta and colleagues identified chimeric antigen receptor (CAR) T cell biomarkers that may predict the success or failure of CAR therapy in patients with refractorychroniclymphoblastic leukemia (CLL). These findings open new prospects for improving T cell product manufacturing and the management of patients with CLL undergoing T cell-based therapies.

引用

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页码：729 / 731

页数：3

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