Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study

被引：16
|
作者：
De Cecio, Rossella [1 ]
Cantile, Monica [1 ]
Collina, Francesca [1 ]
Marra, Laura [1 ]
Santonastaso, Clemente [1 ]
Scaffa, Cono [2 ]
Botti, Gerardo [1 ]
Losito, Nunzia Simona [1 ]
机构：
[1] Ist Nazl Tumori Fdn G Pascale, Pathol Unit, I-80131 Naples, Italy
[2] Ist Nazl Tumori Fdn G Pascale, Dept Gynecol Oncol, I-80131 Naples, Italy
来源：
JOURNAL OF OVARIAN RESEARCH | 2014年 / 7卷
关键词：
Brenner tumors; Immuno-profile; Molecular analyses; GENETIC-ANALYSIS; PATHOGENESIS; ORIGIN;
D O I：
10.1186/s13048-014-0101-7
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Background: Borderline Brenner tumor of the ovary is a rare entity characterized by papillary structures with a fibro-vascular core, covered by a transitional epithelium, and by the absence of stromal infiltration. It is associated, by definition, with a benign component of Brenner tumor. Case: We report a case of a 68-year-old woman, with a right ovarian mass, whose morphology and immuno-profile were consistent with the diagnosis of a borderline Brenner tumor. Immunohistochemistry carried out on selected markers may help to formulate the diagnosis, more than the molecular analyses.
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页数：5
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