Borderline Brenner tumor of the ovary: a case report with immunohistochemical and molecular study

被引：16

作者：

De Cecio, Rossella ^{[1
]}

Cantile, Monica ^{[1
]}

Collina, Francesca ^{[1
]}

Marra, Laura ^{[1
]}

Santonastaso, Clemente ^{[1
]}

Scaffa, Cono ^{[2
]}

Botti, Gerardo ^{[1
]}

Losito, Nunzia Simona ^{[1
]}

机构：

[1] Ist Nazl Tumori Fdn G Pascale, Pathol Unit, I-80131 Naples, Italy

[2] Ist Nazl Tumori Fdn G Pascale, Dept Gynecol Oncol, I-80131 Naples, Italy

来源：

JOURNAL OF OVARIAN RESEARCH | 2014年 / 7卷

关键词：

Brenner tumors; Immuno-profile; Molecular analyses; GENETIC-ANALYSIS; PATHOGENESIS; ORIGIN;

D O I：

10.1186/s13048-014-0101-7

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Background: Borderline Brenner tumor of the ovary is a rare entity characterized by papillary structures with a fibro-vascular core, covered by a transitional epithelium, and by the absence of stromal infiltration. It is associated, by definition, with a benign component of Brenner tumor. Case: We report a case of a 68-year-old woman, with a right ovarian mass, whose morphology and immuno-profile were consistent with the diagnosis of a borderline Brenner tumor. Immunohistochemistry carried out on selected markers may help to formulate the diagnosis, more than the molecular analyses.

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页数：5

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