Hepatitis B virus and intrahepatic cholangiocarcinoma

被引：14

作者：

Gatselis, Nikolaos K.

Tepetes, Konstantinos

Loukopoulos, Argirios

Vasiou, Katerina

Zafiriou, Athanasios

Gioti, Chrisoula

Dalekos, Georgios N. ^{[1
]}

机构：

[1] Univ Thessaloniki, Sch Med, Acad liver Unit & Res Lab Internal Med, Dept Med, GR-41222 Larisa, Greece

[2] Univ Thessaloniki, Sch Med, Dept Surg, GR-41222 Larisa, Greece

[3] Univ Thessaloniki, Sch Med, Dept Radiol, GR-41222 Larisa, Greece

来源：

CANCER INVESTIGATION | 2007年 / 25卷 / 01期

关键词：

cholangiocarcinoma; HBV; HCV; cirrhosis;

D O I：

10.1080/07357900601130722

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Intrahepatic cholangiocarcinoma ( ICC) is a rare type of primary liver cancer that arises from intrahepatic bile ducts. Its etiopathogenesis has been considered to be independent of the presence of chronic viral hepatitis infections or cirrhosis. These factors, particularly the hepatitis C virus, have been reported to play a role in the development of cholangiocarcinoma in a few studies, with inconclusive results. We report 2 cases of ICC that presented with a background of hepatitis B virus ( HBV) infection and discuss the possible pathophysiological relationships between ICC and HBV infection, with an emphasis on the x gene of HBV.

引用

页码：55 / 58

页数：4

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