Synthesis of 2-acylfurans from 3-(1-alkynyl)-2-alken-1-ones via the oxidation of gold-carbene intermediates by H2O2

被引：70
|
作者：
Wang, Tao [1 ]
Zhang, Junliang [1 ]
机构：
[1] E China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Dept Chem, Shanghai 200062, Peoples R China
来源：
DALTON TRANSACTIONS | 2010年 / 39卷 / 18期
基金：
中国国家自然科学基金;
关键词：
HIGHLY SUBSTITUTED FURANS; PALLADIUM-CATALYZED CYCLIZATION; C-BOND FORMATION; EFFICIENT SYNTHESIS; DOMINO REACTIONS; POLYSUBSTITUTED FURANS; TETRASUBSTITUTED FURANS; ORGANIC-SYNTHESIS; ALLENYL KETONES; 2-(1-ALKYNYL)-2-ALKEN-1-ONES;
D O I：
10.1039/c0dt00024h
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
An efficient approach to 2,4,5-trisubstituted 2-acylfurans is described: treating 3-(1-alkynyl)-2-alken-1-ones with AuCl3 in DCM at rt in the presence of H2O2 afforded good yields of 2-acylfurans.
引用
收藏
页码：4270 / 4273
页数：4
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